BACKGROUND The objective of this study was to investigate HLA-DRB1*and DQB1* allelic polymorphisms in Iranian patients with hydatidose. This is the first survey dealing with the correlation between HLA-DRB1* and DQB1* alleles and cystic echinococcosis in Iranian patients. METHODS The study was carried out on 56 patients with confirmed cystic echinococcosis and 30 apparently healthy individual...

The diagnosis of alveolar echinococcosis, caused by the larval stage of Echinococcus multilocularis, is often difficult and almost always possible only in the later stages of the disease. In this study, we aimed to evaluate the findings of Doppler ultrasonography images for the diagnosis of intraabdominal non-visceral alveolar echinococcosis in Meriones unguiculatus. Six infected animals were s...

AIM To investigate a safer way to set up the disease model of cystic echinococcosis without contamination risk and develop a novel experimental murine model of hepatic cystic echinococcosis. METHODS C57B/6 mice were injected with human protoscolices of three different concentrations via the portal vein. The mice were followed for 10 mo by ultrasound, gross anatomy, and pathological and immuno...

A 58-year-old male from North-East China who was an immigrant worker for 4 years, presented with a cystic mass of the liver that was incidentally detected on abdominal ultrasound. Blood liver battery showed no abnormal findings and stool helminth was negative. Serologic markers for hepatitis A, B, and C virus were all negative and blood levels of tumor markers including α-fetoprotein, carcinoem...

Introduction Infections caused by metacestode stage of the Echinococcus granulosus in humans result in disease named cystic echinococcosis. Aim To present the outcomes of patients treated surgically for cystic echinococcosis of the liver. Material and methods One hundred and nineteen patients treated in the period between 1989 and 2014 due to E. granulosus infection in the Department of Gen...

BACKGROUND Echinococcosis in humans is a disease caused by the larvae of Echinococcus granulosus (E. granulosus) and Echinococcus multilocularis (E. multilocularis). Serological tests are valuable, especially in the clarification of unexplained clinical findings and imaging methods. For this reason, indirect hemagglutination (IHA), latex agglutination, immunoelectrophoresis, immunoblotting, imm...

BACKGROUND/AIM To develop a novel polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) protocol using a new genomic marker sequence and a novel set of restriction enzymes in order to detect and discriminate 2 Echinococcus species, E. granulosus and E. multilocularis, found in formalin-fixed paraffin-embedded (FFPE) human tissues. MATERIALS AND METHODS DNA was isolated...

background: haemonchosis has a negative effect on the farming industry throughout the world, especially in the tropic and sub-tropic countries. the present study was carried out to differentiate haemonchus species from its main hosts in iran, including sheep, goat and camel.   methods: the identification took place based on the morphometrics of the spic-ules and molecular characters. two hundre...

China is one of the world’s most highly endemic countries for the cestode zoonosisechinococcosis. In the northwest of the country, both Echinococcus granulosus and E.multilocularis are transmitted between domestic livestock or wildlife hosts respectively, over vast and relatively remote regions. Traditional pastoralist communities of Tibetan, Kazakh and Mongol ethnic minorities appear to be mos...