Abstract Fasting is a popular dietary strategy because it grants numerous advantages, and redox regulation one mechanism involved. However, the precise changes with respect to species, organelles tissues remain unclear, which hinders understanding of metabolic mechanism, exploring precision map under various statuses great significance. Twelve redox-sensitive C. elegans strains stably expressin...

Wegener's granulomatosis, microscopic polyangiitis, and renal limited vasculitis are associated with circulating anti-neutrophil cytoplasm antibodies and are an important cause of rapidly progressive glomerulonephritis. This review gives an account of recent advances in the understanding of the pathogenesis underlying these conditions and how these may lead to future treatments. Consideration i...

We track the motion of individual fluorescently labeled mRNA molecules inside live E. coli cells. We find that the motion is subdiffusive, with an exponent that is robust to physiological changes, including the disruption of cytoskeletal elements. By modifying the parameters of the RNA molecule and the bacterial cell, we are able to examine the possible mechanisms that can lead to this unique t...

We have used size-fractionated, fluorescent dextrans to probe the structure of the cytoplasmic ground substance of living Swiss 3T3 cells by fluorescence recovery after photobleaching and video image processing. The data indicate that the cytoplasm of living cells has a fluid phase viscosity four times greater than water and contains structural barriers that restrict free diffusion of dissolved...

Background: The most important factor affecting the efficiency of somatic cell nuclear transfer (SCNT) is the initial quality of the oocyte. Since the abattoir-derived oocytes are heterogeneous in quality, selection of cohort fully grown/competent oocytes is necessary for proper development of SCNT embryos. Materials and Methods: Glucose-6-phosphate dehydrogenase (G6PDH) is actively expressed i...