We isolated a thermophile, Bacillus sp. YM-1 which abundantly produced the thermostable D-amino acid aminotransferase (EC 2.6.1.21; D-AAT), and cloned the enzyme gene into E. coli. The primary structure of D-AAT was found to be homologous with that of branched-chain L-amino acid aminotransferase (EC 2.6.1.42; BCAT) of E. coli. Both enzymes are unique in their stereospecificity of proR C-4' hydr...

D-amino acids have been detected in a variety of peptides synthesized by animal cells. These include opiate and antimicrobial peptides from amphibian skin, neuropeptides from snail ganglia, a hormone from crustaceans, and a constituent of a spider venom. cDNA cloning has shown that at those positions where a D-amino acid is found in the end-product, a normal codon for the corresponding L-amino ...

Background and Aims: Amino acids have different effects on the growth of some dermatophytes. Some may increase whereas others maydecrease their growth. The concentration of some amino acids is also an important factor for their effects. Materials and Methods: To investigate the effects of L-amino acids on the growth of six species of dermatophytes including Epidermophyton floccosum, Microspor...