Interleukin (IL)-33 is an important member of the IL-1 family that has pleiotropic activities in innate and adaptive immune responses in host defense and disease. It signals through its ligand-binding primary receptor ST2 and IL-1 receptor accessory protein (IL-1RAcP), both of which are members of the IL-1 receptor family. To clarify the interaction of IL-33 with its receptors, we determined th...

Reed-Solomon codes are a class of non-binary cyclic codes which have strong burst and erasure error correction capabilities. Their current uses include deep-space communications, compact disc recordings, cellular communications, and digital broadcast[1]. Their popularity stems in part from the existence of encoding and decoding algorithms that are simple to implement in hardware. In addition to...

The aim of this study is to evaluate the validity and reliability of the Mandibular Function Impairment Questionnaire (MFIQ) (Portuguese version). Face and content validity of the Portuguese version were performed. To assess reproducibility of the data gathered with MFIQ, it was applied to 62 individuals who completed the questionnaire on two occasions. Validity and reliability of the data gath...

In this short note, we give an affirmative answer to a question of Ayad from [1]. 1. Main result In [1], Mohamed Ayad asked to prove that there does not exist an odd prime p and two positive divisors d1 and d2 of (p2 +1)/2 such that d1 +d2 = p+ 1. In this note, we prove a bit more, namely: Theorem 1.1. There does not exist an odd integer n > 1 and two positive divisors d1 and d2 of (n2 + 1)/2 s...

The large glycoprotein von Willebrand factor (vWF) serves an important role in orchestrating the blood vessel’s response to injury. It is released from activated endothelial cells and forms long multimeric strings that bind exposed extracellular matrix and circulating platelets and thereby initiate the formation of a platelet plug sealing the wound. Central to this process is the rapid transiti...

We discuss the question of entanglement versus separability of pure quantum states in direct product Hilbert spaces, and the relevance of this issue to physics. Different types of separability may be possible, depending on the particular factorization of the Hilbert space. A given orthonormal basis set for a Hilbert space is defined to be of type (p,q) if p elements of the basis are entangled a...

Engineered red blood cells (RBCs) expressing viral receptors could be used therapeutically as traps, RBCs lack nuclei and other organelles required for replication. However, expression of on is difficult to achieve since mature erythrocytes the cellular machinery synthesize proteins. Herein, we show that combination a powerful erythroid-specific system transgene codon optimization yields high l...

The help project proposes a model of data-parallel programming allowing a programmer to develop an algorithm the nearest of his thought. Usually, for many parts of a data-parallel program, the manipulations of data could be modelized as geometrical migrations inside a cartesian reference space. We de ne the language C-help in the frame of explicit data-parallel languages, the communications and...

Primary mediastinal large B-cell lymphoma (PMBL) cells depend on the constitutive activity of NF-κB and STAT transcription factors, which drive expression multiple molecules essential for their survival. In a molecularly related malignant tumor (classic Hodgkin lymphoma), Reed-Sternberg overexpress oncogenic (proviral integration site Moloney murine leukemia virus (PIM) 1, 2, 3 kinases in NF-κB...