It is now increasingly realized that the underlying mechanism which governs aging (ageing) is a complex interplay of genetic regulation and damage-accumulation. “Aging as a result of accumulation of „faults‟ on cellular and molecular levels”, has been proposed in the damage (fault)-accumulation theory. However, this theory fails to explain some aging phenotypes such as fibrosis and premature ag...

Alkaline stress (high pH) severely damages root cells, and consequently, inhibits rice (Oryza sativa L.) seedling growth. In this study, we demonstrate the accumulation of reactive oxygen species (ROS) in root cells under alkaline stress. Seedlings of two rice cultivars with different alkaline tolerances, 'Dongdao-4' (moderately alkaline-tolerant) and 'Jiudao-51' (alkaline-sensitive), were subj...

The biological processes that underlie senescence are of universal biological importance, yet they remain poorly understood. A popular theory proposes that senescence is the result of limited investment into mechanisms involved in the prevention and repair of molecular damage, leading to an accumulation of molecular damage with age. In ants, queen and worker lifespans differ by an order of magn...

In the present investigation, two dimensional elastoplastic finite element analysis was conducted to assess the deformation characteristics of Al 1100 alloy during continuous confined strip shearing (C2S2) process. The results of simulations showed that the plastic strain distribution across the deformed sample is non-uniform irrespective of the amount of friction and C2S2 die angle. The most u...

where Mkk represents the trace components of the moment tensor,  and  are Lame constants. These results imply that the damage evolution and the accumulation of relative crack volume are also estimated from the moment tensor analysis. From moment tensors determined in bending tests of concrete specimens with a notch [Ohtsu & Ohtsuka 1998], the damage and the accumulation of crack volume were e...

Abstract Modern wind turbines have higher rated power and improved capacity factors. This results in very long slender blades which are also designed closer to the material limits. As a consequence, blade test facilities need be upgraded for static fatigue full-scale testing carry larger loads deal with tip deflections. Another aspect is adaption of methods avoid high overloads, can cause prema...