نتایج جستجو برای: danon
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In this paper, we present a data mining based methodology for optimizing the outcome of a batch manufacturing process. Predictive data mining techniques are applied to a multi-year set of manufacturing data with the purpose of reducing the variation of a crystal manufacturing process, which suffers from frequent fluctuations of the average outgoing yield. Our study is focused on specific defect...
The Lysosomal Associated Membrane Protein type-2 (LAMP-2) is an abundant lysosomal membrane protein with an important role in immunity, macroautophagy (MA) and chaperone-mediated autophagy (CMA). Mutations within the Lamp2 gene cause Danon disease, an X-linked lysosomal storage disorder characterized by (cardio)myopathy and intellectual dysfunction. The pathological hallmark of this disease is ...
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