sepsis constitutes an important cause of hospital admission with a high mortality rate. appropriate antibiotic therapy is the cornerstone of therapy in patients with sepsis. although numerous studies have recommended early antibiotic initiation in severe sepsis or septic shock stages of sepsis syndrome, its role in treatment of patients with sepsis who have not entered these stages remains to b...

discussion l. monocytogenes can cause progressive and rapidly fatal infections in the vulnerable persons, with multisystem involvement. since this bacterium is not susceptible to cephalosporines, it will be better to consider effective antimicrobials in the treatment of the possible cases. case presentation a 70-years-old patient with chronic renal failure was admitted to the infectious disease...

background: to determine prospectively the prevalence of anaerobic and aerobic infection in early onset (during 72 hours of age) neonatal sepsis, in tehran vali-e-asr hospital. methods: among all the live birth, neonates suspecting of having septicemia were investigated for isolation of micro­organisms. culture bottle containing enriched tryptic soy broth was used for standard blood culture sys...

sepsis is a significant cause of morbidity and mortality in neonates. the most common pathogens of bacterial sepsis and antibiotic sensitivity patterns vary in different parts of the world. the aim of this study was to determine the most common pathogens and outcome of neonatal sepsis and also antibiotic sensitivity patterns of klebsiella species. a retrospective descriptive study was carried o...

introduction melioidosis is a rapidly fatal infectious disease caused by burkholderia pseudomallei, an agent of potential biothreat, endemic in several parts of india. most melioidosis-induced infected aneurysms are located in the abdominal or thoracic aorta. case presentation we reported two unusual cases of melioidosis resulting in pseudoaneurysm of the descending thoracic aorta. in both case...

BACKGROUND The management of hospital-acquired infections (HAIs) with respect to physician practices remains largely unexplored despite increasing efforts to standardize care. In the present study, we report findings from a 2-month audit of all patients that have undergone cardiac surgery at a large referral center in Atlantic Canada. METHODS All patients who underwent cardiac surgical proced...

Background: Introduction: Searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. There are many biomarkers reported for neonatal sepsis. Haptoglobin is an acute phase reactants which rise in response to infection and injuries. In this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

BACKGROUND Health-care-acquired infections (HAIs) are a leading cause of morbidity and mortality after cardiac surgery. Prior work has identified several patient-related risk factors associated with HAIs. We hypothesized that rates of HAIs would differ across institutions, in part attributed to differences in case mix. METHODS AND RESULTS We analyzed 20 896 patients undergoing isolated corona...

OBJECTIVES We studied the influence of the number of sternotomy mechanical fixation points on deep sternal wound infection (DSWI). METHODS Between September 2007 and February 2011, 2672 patients underwent a standard peri-sternal wire closure following a median sternotomy for a first-time cardiac surgery. Data were collected during the study period. RESULTS The mean age of the patients was 6...

background: serum procalcitonin (pct) levels differ in patients with bacterial or fungal infections and are significantly elevated in patients with gram-negative bacteremia. we evaluated the diagnostic accuracy of different inflammatory markers to discriminate sepsis caused by different pathogens. materials and methods: we included 328 episodes of bacteremia from 292 patients with sepsis and 31...