A method is described for the rapid, economic and non-radioactive examination of DNA samples from hypercholesterolaemic patients for familial defective apolipoprotein B-100, using a modified polymerase chain reaction (PCR) protocol and restriction enzyme isoform genotyping. Because of the high prevalence of familial defective apolipoprotein B-100, which is estimated to be one in 500 in most scr...

In a variety of insurance risk models, ruin-related quantities in the class of expected discounted penalty function (EDPF) were known to satisfy defective renewal equations that lead to explicit solutions. Recent development in the ruin literature has shown that similar defective renewal equations exist for a more general class of quantities than that of EDPF. This paper further extends the ana...

By examining the nature of time limit for right to compensation damage caused by defective products (Article 11 Directive 85/374/EEC – Product Liability Directive) in relation Slovak legal order (Act no. 294/1999 Coll. on implementing EU Directive), authors address question consequences conflict between different language versions Directive. At same time, they examine whether semantic identity ...

Pseudomonas aeruginosa ParA belongs to a large subfamily of Walker-type ATPases acting as partitioning proteins in bacteria. ParA has the ability to both self-associate and interact with its partner ParB. Analysis of the deletion mutants defined the part of the protein involved in dimerization and interactions with ParB. Here, a set of ParA alanine substitution mutants in the region between E67...

To overcome stress, such as resource limitation, an organism often needs to successfully mediate competition with other members of its own species. This may favor the evolution of defective traits that are harmful to the species population as a whole, and that may lead to its dilution or even to its extinction (the tragedy of the commons). Here, we show that this phenomenon can be circumvented ...

in this model, we establish an inventory model to determine the optimal inventory replenishment scheme for the economic production quantity (epq) model for imperfect, deteriorating items with sales return service under multiple production and rework setup. in one cycle, production process can produces the products in m production setups and reworks the defective items in one rework setup. the c...

a r t i c l e i n f o JEL classification: C02 M11 C44 C61 Keywords: Multi-item production system Rotation cycle time Multi-delivery Economic production quantity model Scrap Vendor–buyer integrated system This paper addresses the joint determination of a rotation cycle time and number of shipments for a multi-item economic production quantity (EPQ) model with random defective rate. The classic E...

Abstract The manufacture of In Vitro Fertilization (IVF) needles is subject to the most stringent quality demands. This makes automated inspection challenging due difficulty in reliably classifying conforming and non-conforming (defective) products factors including multidimensional variation their tip geometry lack an explicit standard. addition, developing IVF needle image dataset, which broa...

Quality plays an important role, problems in the number of defects production cause a decrease quality. To prevent this increase defective products, it is necessary to evaluate most types determine causes so that corrective actions are obtained using statistical process control (SPC) methods and with 3 Pareto diagram controllers, charts fishbones. This research intended explore facts about Defe...

The basic assumption in classical production quantity models is that all of the products produced are free defect. But real life, this not always valid. EPQ were examined for situation where proportion defective a random variable and fits certain probability distribution. When literature reviewed, it seen scanning speed accepted as equal to rate. In study, model was developed under condition sm...