LEUNG, PHILIP M.-B., AND QUINTON R. ROGERS. Importance of prepyriform cortex in food-intake response of rats to amino acids. Am. J. Physiol. 221(3): 929-935. 197 1 .-Bilateral electrolytic lesions were placed in the prepyriform cortex of male 230to 250-g rats and their food intake as affected by amino acid imbalance, deficiency, and excessive protein was examined. All rats with such lesions and...

Three experiments were conducted to determine the effects of pelleting and extrusion of feeds on the utilization of phytate P by broilers. The first experiment investigated the effects of pelleting the whole corn-soybean meal (SBM) diet, the corn, or SBM separately on phytate P utilization. The P-deficient basal diet contained 0.5% total P and 0.2% phytate P. Steam pelleting the whole diet, the...

Four chick bioassays were conducted to evaluate the threonine (Thr) replacement value of l-homoserine (HS). Growth rate was increased (P < 0.05) by dietary addition of 800 mg l-HS/kg diet to a purified diet severely deficient in Thr or by the addition of 800 or 1000 mg of l-HS/kg diet to a corn-peanut meal diet distinctly deficient in Thr. The addition of an isomolar level of alpha-ketobutyrate...

I . Three groups of rats of different mean weights were given a diet of milk treated with hydrogen sulphide and supplemented with copper-free minerals and vitamins. Also divided into three groups of similar weights were rats given the same diet supplemented with 500 pg Culweek and stock rats which were given a commercial diet. 2. In a second experiment eight adult female rats were given the Cu-...

BACKGROUND/AIMS Maternal diet may have an effect on the health of the offspring in middle and later life. This study used the laboratory rat as an animal model to examine whether the fibre content of the maternal diet during pregnancy affected subsequent development of colonic diverticula in the offspring fed lifelong fibre deficient or higher fibre diets. METHODS The parents of experimental ...

Simultaneous zinc and vitamin A deficiency are common health problems in developing countries. The objective of this study was to assess effect of supplementation of high zinc or vitamin A on immune function. After three months of feeding with a zinc and vitamin A deficient diet, mice were assigned into four groups which, for additional two months, received a normal or high zinc along with vita...

Vitamin A is involved in regulation of glucose concentrations, lipid metabolism, and inflammation, which are major risk factors for atherogenesis. However, the effect of vitamin A deficiency on atherogenesis has not been investigated. Therefore, the objective of the current study was to examine whether vitamin A deficiency accelerates atherogenesis in apolipoprotein E-deficient mice (apoE(-/-))...

Constitutive expression of a cholesterol-7alpha-hydroxylase (CYP7A1) transgene in LDL receptor-deficient mice blocked the ability of a cholesterol-enriched diet to increase plasma levels of apolipoprotein B-containing lipoproteins. LDL receptor-deficient mice expressing the CYP7A1 transgene exhibited complete resistance to diet-induced hypercholesterolemia and to the accumulation of cholesterol...

We investigated the effects of trace element deficiency on drug-metabolizing enzymes in rats. Weanling rats were fed a selenium-deficient diet (Torula yeast) or a normal diet (0.5μg selenium) until 20 weeks. After six weeks of the selenium-deficient diet, an increase in aniline hydroxylase activity was observed in the selenium-deficient rats, but the activity of aminopyrine N-demethylase was re...

The present study employed an imaging mass spectrometry (IMS) method to evaluate the effect of dietary n – 3 fatty acids on the fatty acid composition in rat brain. Rats were divided into two groups and fed either an n – 3 fatty acid-deficient or adequate diet. We determined the decreased n – 3 fatty acids in the hippocampus of rats fed an n – 3 fatty acid-deficient diet compared to the control...