نتایج جستجو برای: dendrite formation
تعداد نتایج: 530635 فیلتر نتایج به سال:
Zinc-anode-based batteries have been widely studied because of their low cost, high capacity, and energy density. However, the formation dendrites on zinc anode during cycling severely ...
Dendrite formation and growth remains a major obstacle toward high-performance all solid-state batteries using Li metal anodes. The ceramic Li(1+x)Al(x)Ti(2?x)(PO4)3 (LATP) electrolyte shows higher than expected stability against electrochemical decomposition despite bulk electronic conductivity that exceeds recently postulated threshold for dendrite-free operation. Here, transmission electron ...
Introduction Fragile X Syndrome (FXS) is the most common form of inherited mental retardation, caused by a trinucleotide repeat expansion resulting in silencing of the fragile X mental retardation 1 (FMR1) gene in humans. The array of disorders caused by mutations in this single gene includes mental retardation and autistic behaviors. There is much evidence that the protein product, fragile X m...
Nedd4-1 is a "neuronal precursor cell expressed and developmentally downregulated protein" and among the most abundant E3 ubiquitin ligases in mammalian neurons. In analyses of conventional and conditional Nedd4-1-deficient mice, we found that Nedd4-1 plays a critical role in dendrite formation. Nedd4-1, the serine/threonine kinase TNIK, and Rap2A form a complex that controls Nedd4-1-mediated u...
Dendrite branching and spine formation determines the function of morphologically distinct and specialized neuronal subclasses. However, little is known about the programs instructing specific branching patterns in vertebrate neurons and whether such programs influence dendritic spines and synapses. Using knockout and knockdown studies combined with morphological, molecular, and electrophysiolo...
Proper function of the nervous system critically relies on sophisticated neuronal networks interconnected in a highly specific pattern. The architecture of these connections arises from sequential developmental steps such as axonal growth and guidance, dendrite development, target determination, synapse formation and plasticity. Leucine-rich repeat (LRR) transmembrane proteins have been involve...
Activity-dependent specification of neuronal architecture during early postnatal life is essential for refining the precision of communication between neurons. In the spinal cord under normal circumstances, the AMPA receptor subunit GluR1 is expressed at high levels by motor neurons and surrounding interneurons during this critical developmental period, although the role it plays in circuit for...
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