نتایج جستجو برای: dendrosomal curcumin

تعداد نتایج: 11144  

Journal: :Pakistan journal of pharmaceutical sciences 2018
Liandong Hu Qiaofeng Hu Chenchen Yang

In this study a new soluble solid curcumin nanoemulsion powder was prepared using spray-drying technology to improve the solubility and bioavailability of curcumin. The liquid nanoemulsion consisted of curcumin, Capryol 90, Transcutol P, and Cremophor RH40. The solid nanoemulsion was prepared by spray-drying the liquid nanoemulsion in laboratory spray dryer, using lactose as solid carrier. The ...

Journal: :Biological & pharmaceutical bulletin 2013
Qand Agha Nazari Toshiaki Kume Naotaka Izuo Yuki Takada-Takatori Atsushi Imaizumi Tadashi Hashimoto Yasuhiko Izumi Akinori Akaike

Curcumin, a polyphenolic compound extracted from Curcuma longa, has several pharmacological activities such as anticancer, anti-inflammatory, and antioxidant effects. The purpose of this study was to investigate the protective effects of curcumin and THERACURMIN, a highly bioavailable curcumin, against sodium nitroprusside (SNP)-induced oxidative damage in primary striatal cell culture. THERACU...

Journal: :avicenna journal of phytomedicine 0
houshang najafi medical biology research center, kermanshah university of medical sciences, kermanshah, iran. saeed changizi ashtiyani department of physiology, school of medicine, arak university of medical sciences, arak, iran. sayed abolhasan sayedzadeh department of nephrology, emam reza hospital, kermanshah university of medical sciences, kermanshah, iran. zeynab mohamadi yarijani medical biology research center, kermanshah university of medical sciences, kermanshah, iran. sajad fakhri school of pharmacy, kermanshah university of medical sciences, kermanshah, iran.

objectives: curcumin has anti-inflammatory and antioxidative properties. the objective of this study was to investigate the therapeutic effects of curcumin on functional disturbances, oxidative stress, and leukocyte infiltration induced by renal ischemia/reperfusion (i/r). materials and methods: animals were randomly divided into 9 groups. the groups with 24-h reperfusion consisted of sham-24h,...

Journal: :Biochemical pharmacology 2008
Preetha Anand Sherin G Thomas Ajaikumar B Kunnumakkara Chitra Sundaram Kuzhuvelil B Harikumar Bokyung Sung Sheeja T Tharakan Krishna Misra Indira K Priyadarsini Kallikat N Rajasekharan Bharat B Aggarwal

Curcumin, a yellow pigment present in the Indian spice turmeric (associated with curry powder), has been linked with suppression of inflammation; angiogenesis; tumorigenesis; diabetes; diseases of the cardiovascular, pulmonary, and neurological systems, of skin, and of liver; loss of bone and muscle; depression; chronic fatigue; and neuropathic pain. The utility of curcumin is limited by its co...

2013
R. Ravichandran

Curcumin, a bioactive component of turmeric, which is a commonly used spice and nutritional supplement, is isolated from the rhizomes of Curcuma longa Linn. (Zingiberaceae). In recent years, the potential pharmacological actions of Curcumin in inflammatory disorders, cardiovascular disease, cancer, Alzheimer’s disease and neurological disorders have been shown. However, the clinical application...

Journal: :Anticancer research 2004
Seiichiro Fujisawa Toshiko Atsumi Mariko Ishihara Yoshinori Kadoma

The cytotoxicity, ROS (reactive oxygen species)-generation activity and radical-scavenging activity of curcumin and related compounds such as eugenol, eugenol orthodimer (bis-eugenol; 3,3'-dimethoxy-5,5'-di-2-propenyl-1,1'-biphenyl-2,2'-diol) and isoeugenol were investigated. Their cytotoxicity against a human submandibular gland adenocarcinoma cell line (HSG) declined in the order curcumin > i...

Journal: :Molecules 2014
Su-Hyun Mun Sung-Bae Kim Ryong Kong Jang-Gi Choi Youn-Chul Kim Dong-Won Shin Ok-Hwa Kang Dong-Yeul Kwon

Curcumin, a natural polyphenolic flavonoid extracted from the rhizome of Curcuma longa L., was shown to possess superior potency to resensitize methicillin-resistant Staphylococcus aureus (MRSA) to antibiotics. Previous studies have shown the synergistic activity of curcumin with β-lactam and quinolone antibiotics. Further, to understand the anti-MRSA mechanism of curcumin, we investigated the ...

Journal: :Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2013
Ravinder Singh Hanne Hjorth Tønnesen Solveig Kristensen Kristian Berg

In order to apply curcumin as a photosensitizer in photodynamic therapy (PDT) one needs a formulation that can solubilize and stabilize the compound. Pluronics® (Pluronic) are reported to both solubilize and stabilize curcumin against hydrolytic degradation. The aim of the present work was therefore to investigate the influence of Pluronic formulation on the photocytotoxicity of curcumin. Inter...

Journal: :The Journal of biological chemistry 2005
Fusheng Yang Giselle P Lim Aynun N Begum Oliver J Ubeda Mychica R Simmons Surendra S Ambegaokar Pingping P Chen Rakez Kayed Charles G Glabe Sally A Frautschy Gregory M Cole

Alzheimer's disease (AD) involves amyloid beta (Abeta) accumulation, oxidative damage, and inflammation, and risk is reduced with increased antioxidant and anti-inflammatory consumption. The phenolic yellow curry pigment curcumin has potent anti-inflammatory and antioxidant activities and can suppress oxidative damage, inflammation, cognitive deficits, and amyloid accumulation. Since the molecu...

2010
Bachar Zebib Zéphirin Mouloungui Virginie Noirot

The purpose of present study was to stabilize curcumin food pigment by its complexation with divalent ions like (Zn(2+), Cu(2+), Mg(2+), Se(2+)), in "green media" and evaluate its stability in vitro compared to curcumin alone. The curcumin complexes were prepared by mechanical mixture of curcumin and sulfate salts of each metal (metal : curcumin 1/1mol) into unconventional and nontoxic glycerol...

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