diabetes mellitus is a chronic disease which affects the healing ability of the pulp and periodontium. the aim of the present study was to assess the histopathologic response of dental pulp to pulp capping using mta or cem cement in diabetic rats. thirty two wistar male rats aged between 8 and 10 weeks (weight: 200-250g) were divided into two groups of diabetic (n=16) and healthy (n=16) animals...

BACKGROUND Precise assessment of dental pulp anatomy is of an extreme importance for a successful endodontic treatment. As standard radiographs of teeth provide very limited information on dental pulp anatomy, more capable methods are highly appreciated. One of these is 3D magnetic resonance (MR) microscopy of which diagnostic capabilities in terms of a better dental pulp anatomy assessment wer...

The regenerative potential of dental pulp is very limited in mature teeth. However, our improved understanding of pulpal inflammation and repair and improved dental materials and technologies make vital pulp therapy a viable alternative to root canal treatment. This article explores our knowledge in this regard and the future potential of saving or even regenerating the pulp as a routine dental

BACKGROUND AND OBJECTIVE Dental pulp repair is a common process triggered by microbial and mechanical challenges. Matricellular modulators, such as periostin, are key for extracellular matrix stability and tissue healing. In the scope of the dental pulp, periostin expression has been reported during development and active dentinogenesis. However, the specific dental pulp cell population capable...

Dental Caries affects approximately 90% of the world's population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality. Tissue engineering can potentially solve this problem by enabling regeneration of a functional pulp tissue. Dental pulp stem cells (DPSCs) have been shown to be an excellent source for pul...

stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type i diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations and cancer. in addition to their potential use to treat systemic diseases, stem cell-based therapy also provides a powerful tool to treat oral and dental diseases such as cra...

Innate immunity represents the first line of defence against infectious agents and is essential for the detection of pathogens invading the host. Unless adaptive immunity, innate immunity is considered as non-specific as it is antigen-independent and reacts similarly to a variety of micro-organisms. It is responsible for mounting potent inflammatory responses that bring to infected tissues a va...

Radiograph plays the major role of diagnosis, treatment and surgery in Dental field. There are many types Intra extra oral radiographs which Panoramic helps visualising full view cavity. Pulpitis is dental diseases caused due to inflammation pulp from untreated caries, trauma or multiple restorations leads Apical Periodontitis. To predict severity vitality has be evaluated. Radiographs dentist ...

Human dental pulp cells (HDPCs) play a crucial role in dental pulp inflammation. Pannexin 3 (Panx3), a member of Panxs (Pannexins), has been recently found to be involved in inflammation. However, the mechanism of Panx3 in human dental pulp inflammation remains unclear. In this study, the role of Panx3 in inflammatory response was firstly explored, and its potential mechanism was proposed. Immu...