Extraction of essential oils from medicinal plants has received researcher’s attention as it has a wide variety of applications in different industries. In this study, ultrasonic method has been used to facilitate the extraction of active ingredient anethole from fennel seeds. Effect of different parameters like extraction time (20, 40, and 60 min), power (80, 240, and 400 Watts) and solid part...

Problem solving is a key activity for any innovative company. As the dialectical approach has shown its efficiency in problem solving, the starting point of our work is the use of contradiction in problem formulation stage. In this article, we analyse the possibility to use information brought by a Design of Experiments (DoE) to formulate a contradiction. Constraint Satisfaction Problem is empl...

A systematic design of experiments (DOE) approach was used to optimize the perfusion process of a tri-axial bioreactor designed for translational tissue engineering exploiting mechanical stimuli and mechanotransduction. Four controllable design parameters affecting the perfusion process were identified in a cause–effect diagram as potential improvement opportunities. A screening process was use...

A systematic design of experiments (DOE) approach was used to optimize the perfusion process of a tri-axial bioreactor designed for translational tissue engineering exploiting mechanical stimuli and mechanotransduction. Four controllable design parameters affecting the perfusion process were identified in a cause-effect diagram as potential improvement opportunities. A screening process was use...

This paper discusses the suitability of the Design of Experiments (DOE) methodology for storage performance tuning. The DOE estimates the main and interaction effects of three major storage factors viz, Cache Partition Size (CPS),LUN Strip Size (LSS) and Cache Segment Size (CSS) settings of an enterprise level storage system on the overall storage performance. Other factors influencing performa...

This paper attends to demonstrate the usefulness of Design of Experiments (DOE) method in magnetic refrigeration (MR) understanding and optimization. A numerical DOE is applied to a simple 1D finite difference model describing an Active Magnetic Regenerative Refrigeration (AMRR) system. The heat transfer fluid is water, the regenerator consists of stacked gadolinium plates and the model is base...

Research in chemical engineering requires experiments, which are often expensive, time-consuming, and laborious. Design of experiments (DoE) aims to extract maximal information from a minimum number experiments. The combination DoE with machine learning leads the field active learning, results more flexible, multi-dimensional selection Active has not yet been applied reaction modeling, as most ...

Design of experiments (DOE) has become an essential tool for validation of medical manufacturing processes. Kim and Kalb provided a good overview of the techniques. They say “the process should be challenged to discover how outputs change as variables fluctuate within allowable limits.” This article shows how we challenged our durable medical device – a paraffin heat-therapy bath. We first ran ...