Background: The purpose of this study was to determine the relationship between early onset sepsis and increased levels of C-reactive protein (CRP) and interleukin-6 (IL-6) in cord plasma. Methods: A prospective study was conducted in 141 premature infants delivered with gestational ages of 26-35 weeks. IL-6 and CPR were measured by enzyme-linked immunoassay in the cord plasma of the neonates. ...

In daily clinical practice the diagnosis of sepsis is imprecise and often delayed. In part, this is because the diagnosis is based on a clinical picture of signs and symptoms. This basis has significant implications, as there is evidence that early events in sepsis may determine outcome. A more objective set of measurements for confirming the diagnosis of sepsis has long been sought. Several se...

Neonatal sepsis is a life-threatening disease. Early diagnosis essential, but no single marker of infection has been identified. Sepsis activates coagulation cascade with simultaneous production the D-dimers due to lysis fibrin. D-dimer test reflects activation system.

INTRODUCTION Consensus criteria for pediatric severe sepsis have standardized enrollment for research studies. However, the extent to which critically ill children identified by consensus criteria reflect physician diagnosis of severe sepsis, which underlies external validity for pediatric sepsis research, is not known. We sought to determine the agreement between physician diagnosis and consen...

Although malaria is endemic in India, congenital malaria is not very common. Congenital malaria is a very rare condition in both endemic and nonendemic areas. We report a case of congenital malaria in a six-day-old neonate with fever and splenomegaly. The diagnosis was picked up accidentally on a peripheral smear examination. Congenital malaria should be kept as differential diagnosis of neonat...

current study determined the overall incidence, common causes as well as main predictors of this final diagnosis among neonates admitted to a rural district hospital in iran. this study was conducted on 699 neonates who were candidate for admission to the nicu. study population was categorized in the case group, including patients exposed to final diagnosis of neonatal seizures and the control ...

background: the purpose of this study was to determine the relationship between early onset sepsis and increased levels of c-reactive protein (crp) and interleukin-6 (il-6) in cord plasma.   methods: a prospective study was conducted in 141 premature infants delivered with gestational ages of 26-35 weeks. il-6 and cpr were measured by enzyme-linked immunoassay in the cord plasma of the neonates...