INTRODUCTION Verruciform xanthoma is a rare, benign lesion characterized by hyperkeratosis and aggregates of foam cell macrophages. Here, we describe a case of verruciform xanthoma on the scrotum, in which the immunohistochemical localization of monocyte chemoattractant protein-1, a chemokine of the C-C or beta family that has been shown to induce the recruitment of monocytes for injured tissue...

Introduction Xanthoma disseminatum (XD) is a rare, benign, non-Langerhans cell histiocytic disorder with unknown etio-pathology. It manifests with multiple, grouped, red-brown to yellow papules and nodules involving the skin, mucous membranes, and internal organs with a predilection for flexures and the face. Case Report We report a patient who presented with disseminated xanthomatous papules...

Xanthomas are localized lipid deposits in the skin, tendons and subcutaneous tissue associated with lipid abnormality. The hyperlipidemia responsible for this disorder can be caused by a primary genetic defect, a secondary disorder, or both. That kind of skin exanthema may be the first signal of cardiovascular risk. We present a 24-year-old woman with a skin eruption that had appeared a few mon...

Bone xanthoma is a rare disease due to the presence of cholesterol deposits in the bone. We report a case of a 56-year-old patient who was hospitalized in orthopedic department for fracture on the left humerus. Histological examination of bone biopsy performed at this site has objectified cholesterol deposits. Laboratory tests showed hypercholesterolemia with hypertriglyceridemia. The diagnosis...

History A two-month-old girl with unremarkable birth history presented with sudden onset of erythematous papules on the limbs and face for one week. There was no systemic upset, and she remained asymptomatic. Her sister had a history of hypertriglyceridaemia under treatment. The patient's other family members enjoyed good physical health and there was no family history of premature coronary hea...

Vol. 27, No. 6, 2015 769 Received December 2, 2014, Revised January 14, 2015, Accepted for publication February 5, 2015 Corresponding author: Il-Hwan Kim, Department of Dermatology, Korea University Ansan Hospital, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, Korea. Tel: 82-31-412-5986, Fax: 82-31-412-5985, E-mail: kumcihk@ korea.ac.kr This is an Open Access article distributed under the terms of t...