Background: Symbol Digit Modalities Test (SDMT) is a simple pencil-and-paper substitution task that measures divided attention, visual scanning and processing speed. It sensitive to cognitive impairment in wide variety of neuropsychiatric conditions. Extant normative data for the SDMT, mainly based on Western populations, may not be applicable Sri Lankans. 
 Aims: We aimed create sex-, age...

We investigated how induced blur affects performance on the Trail Making Test and Digit Symbol Test routinely used in occupational therapy cognitive evaluations. The study used a factorial design with both age (young and old adults) and simulated blur levels of near visual acuity (20/50 and 20/100) manipulated between participants. A sample of 124 healthy, community-living adults was used in th...

Objective: The aim of this study was to investigate whether people exposed to the Chinese Famine in fetal period or in multiple stages of childhood are associated with cognitive decline in adulthood. Furthermore, the nutritional environment of adulthood was explored as an important factor in this correlation. Methods: 1162 adults born between 1952 and 1964 were recruited. They were divided into...

background: exposure to organic solvents is common among workers. objective: to assess neurobehavioral effects of long-term exposure to organic solvents among rubber workers in tehran, iran. methods: across-sectional study was conducted on 223 employees of a rubber industry. the participants completed a data collection sheet on their occupational and medical history, and demographic characteris...

Nine patients who were admitted to Purdysburn Hospital with a clinical diagnosis of Korsakoff's psychosis were subjected to a series of psychometric tests, to electroencephalography (including P3 auditory evoked potential) and to computerised axial tomography. When compared with controls, the experimental group differed significantly in their psychometric scores in all but the comprehension, vo...

OBJECTIVE To examine associations between inflammation and cognitive performance in African Americans and Caucasians. METHODS The sample included 59 African Americans and 219 Caucasians ≥  50 years old who had a baseline visit at the Emory/Georgia Tech Center for Health Discovery and Well Being. Peripheral levels of inflammation (interleukin-6, interleukin-8, C-reactive protein, and tumor nec...

CONTEXT The likelihood of conversion to Alzheimer disease (AD) in mild cognitive impairment (MCI) and the "optimal" early markers of conversion need to be established. OBJECTIVES To evaluate conversion rates to AD in subtypes of MCI and to identify neuropsychological measures most predictive of the time to conversion. DESIGN Patients were followed up semiannually and controls annually. Subt...

Whether long-term blood pressure (BP) variability throughout young adulthood is associated with cognitive function in midlife remains uncertain. Using data from the Coronary Artery Risk Development in Young Adults (CARDIA), which recruited healthy young adults aged 18 to 30 years (mean age, 25 years) at baseline (Y(0)), we assessed BP variability by SD and average real variability (ARV) for 25 ...