This paper reports a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio for generating linear concentration profiles as well as logarithmic concentration profiles spanning 3 and 6 orders of magnitude. The microfluidic networks were composed of thin fluidic-resistance microchannels with 160 to 730 microm(2) cross-sectional areas and thick diffusio...

Microchannels typically have rectangular cross-sections, whereas biological channels, such as blood vessels and airways, circular cross-sections. The difference in cross-sections causes different fluidic behaviors, resulting differences between behavior microchannels channels. To simulate vitro, cross-sectional are required. We developed a microchannel with smooth channel wall, free from cracks...

Honeycombs with thermal expansion coefficients equal to zero are described analytically. The two dimensional lattice microstructure designs described are made of positive expansion materials. This work builds upon previous results, and provides further analysis into creating an optimal rib cross section. The design of ribs with Tee shaped and I shaped cross sections is developed. The behavior o...

We present a lithography-free procedure for fabricating intrinsically three-dimensional microchannels within PDMS elastomers using nylon monofilament molds. embedded monofilaments in an uncured composite to fabricate straight channels of desired length, use as molds form the microchannels. Next, we fabricated two layer devices consisting dialysis membranes, which preconcentrate specific protein...

We developed a dual-compartment neurofluidic system with inter-connecting microchannels to connect neurons from their respective compartments, placed on a planar microelectrode arrays. The design and development of the compartmented microfluidic device for neuronal cell culture, protocol for sustaining long-term cultures, and neurite growth through microchannels in such a closed compartment dev...

Microscale fluid dynamics has received intensive interest due to the emergence of MicroElectro-Mechanical Systems (MEMS) technology. When the mean free path of the gas is comparable to the channel’s characteristic dimension, the continuum assumption is no longer valid and a velocity slip may occur at the duct walls. Non-circular cross sections are common channel shapes that can be produced by m...

in this paper, a new design of optical channel drop filter based on two- dimensional photonic crystal ring resonators with triangular lattice is proposed. the rods of this structure is silicon with the refractive index nsi=3.46 and the surrounding environment is air with the refractive index of nair=1.the widest photonic band gap obtains for the filling ratio of r/a = 0.2. the filter’s transmis...