نتایج جستجو برای: dimers

تعداد نتایج: 15260  

Journal: :Clinical Medicine 2019

Journal: :The Annals of Probability 2020

Journal: :Nature Catalysis 2018

Journal: :Current Opinion in Cell Biology 2021

The stochastic switching between microtubule growth and shrinkage is a fascinating unique process in the regulation of cytoskeleton. To understand it, almost all attention has been focused on ends. However, recent research revived idea that tubulin dimers can also be exchanged protofilaments along shaft, thus repairing protecting it from disassembly. Here, we review describing this phenomenon, ...

Journal: :Physical Chemistry Chemical Physics 2021

Conformational heterogeneity leads to different excited state relaxation pathways in flexibly-linked DPP-dimers.

Journal: :Journal of inorganic biochemistry 2008
Kristina O Pazehoski Tyler C Collins Robert J Boyle Michael I Jensen-Seaman Charles T Dameron

Protein dimerization is essential for cellular processes including regulation and biosignalling. While protein-protein interactions can occur through many modes, this review will focus on those interactions mediated through the binding of metal ions to the proteins. Selected techniques used to study protein-protein interactions, including size exclusion chromatography, mass spectrometry, affini...

Journal: :Current Biology 2002
Philip C Biggin

Recent structural studies show, not only how the desensitization of a ligand-gated ion channel with bound agonist can be rationalized in terms of subunit-subunit instability, but also how a previously unknown mode of interaction may provide clues into how the receptor is tetramerically assembled in vivo.

Journal: :Physical Review Letters 2021

The ground-state properties of two-component bosonic mixtures in a one-dimensional optical lattice are studied both from few- and many-body perspectives. We rely directly on microscopic Hamiltonian with attractive intercomponent repulsive intracomponent interactions to demonstrate the formation quantum liquid. reveal that its stability can be interpreted terms finite-range between dimers. deriv...

Journal: :The Biochemical journal 2014
Tiernan T O'Malley Nur Alia Oktaviani Dainan Zhang Aleksey Lomakin Brian O'Nuallain Sara Linse George B Benedek Michael J Rowan Frans A A Mulder Dominic M Walsh

Dimers of Aβ (amyloid β-protein) are believed to play an important role in Alzheimer's disease. In the absence of sufficient brain-derived dimers, we studied one of the only possible dimers that could be produced in vivo, [Aβ](DiY) (dityrosine cross-linked Aβ). For comparison, we used the Aβ monomer and a design dimer cross-linked by replacement of Ser²⁶ with cystine [AβS26C]₂. We showed that s...

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