نتایج جستجو برای: direct genotyping

تعداد نتایج: 447487  

Journal: :Annals of the rheumatic diseases 2012
Eugénie Koumakis Julien Wipff Philippe Dieudé Barbara Ruiz Matthieu Bouaziz Lucile Revillod Mickaël Guedj Jörg H W Distler Marco Matucci-Cerinic Marc Humbert Gabriella Riemekasten Paolo Airo Inga Melchers Eric Hachulla Daniele Cusi H-Erich Wichmann Nicolas Hunzelmann Kiet Tiev Paola Caramaschi Elisabeth Diot Otylia Kowal-Bielecka Giovanna Cuomo Ulrich Walker László Czirják Nemanja Damjanov Sara Lupoli Costanza Conti Martina Müller-Nurasyid Ulf Müller-Ladner Valeria Riccieri Jean-Luc Cracowski Franco Cozzi Vasiliki Kalliopi Bournia P Vlachoyiannopoulos Gilles Chiocchia Catherine Boileau Yannick Allanore

INTRODUCTION Systemic sclerosis (SSc)-related pulmonary arterial hypertension (PAH) has emerged as a major mortality prognostic factor. Mutations of transforming growth factor beta (TGFβ) receptor genes strongly contribute to idiopathic and familial PAH. OBJECTIVE To explore the genetic bases of SSc-PAH, we combined direct sequencing and genotyping of candidate genes encoding TGFβ receptor ...

2016
Yongqing Tong Bei Liu Hui Liu Hongyun Zheng Jian Gu Hang Liu Min Lin Yali Ding Chunhua Song Yan Li

HBV (hepatitis B virus) genotyping is important in determining the clinical manifestation of disease and treatment response, particularly, in patients with low viral loads. Also, sensitive detection of HBV antiviral drug resistance mutations is essential for monitoring therapy response.Asensitive direct sequencing method for genotyping and the drug resistance mutation detection of low levels of...

Journal: :Journal of the American College of Cardiology 2010

Journal: :Agrarnaâ nauka 2023

Relevance . The etiological agent in the development of persistent lymphocytosis and lymphosarcoma cattle is Bovine leukemia virus Phylogenetic analysis sequenced nucleotide sequences BLV env -gene locus main, but not only, approach to pathogen genotypic classification. Metods aim study was identify single-nucleotide polymorphisms -gene, considered as diagnostically significant for SNP genotypi...

Journal: :iranian journal of basic medical sciences 0
iradj ashrafi tamai bu ali sina university, hamedan, iran research and training center of imam khomeini hospital, tehran, iran taghi zahraei salehi department of microbiology and immunology, faculty of veterinary medicine, university of tehran, tehran, iran aghil sharifzadeh mycology research center, faculty of veterinary medicine, university of tehran, tehran, iran hojjatollah shokri faculty of veterinary medicine, amol university of special modern technologies, amol, iran ali reza khosravi mycology research center, faculty of veterinary medicine, university of tehran, tehran, iran

objective(s): candidiasis infection caused by candida albicans has been known as a major problem in patients with immune disorders. the objective of this study was to genotype the c. albicans isolates obtained from oral cavity of patients with positive human immunodeficiency virus (hiv+) with or/and without oropharyngeal candidiasis (opc). materials and methods:a total of 100 c. albicans isolat...

Journal: :iranian journal of parasitology 0
bahram nikmanesh department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran. hossein mirhendi department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran. zohreh ghalavand iranian tissue bank & research center, tehran university of medical science, tehran, iran. masoud alebouyeh gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, iran. mitra sharbatkhori department of parasitology, school of medicine, golestan university of medical science, gorgan, iran. eshratbeigom kia department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran.

background: the present study was aimed to investigate molecular diversity of echino-coccus granulosus isolates collected from human clinical samples using two mitochondrial genes cox1 and nad1 in iran . methods: forty seven human hydatid cysts were collected through surgery from two hospitals in tehran during 2010-2012. to determine the fertility of protoscoleces, the cyst fluids were subjecte...

Journal: :iranian journal of parasitology 0
m dousti dept. of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran. j abdi dept. of medical parasitology, school of medicine, ilam university of medical sciences, ilam, iran s bakhtiyari dept. of medical biochemistry, school of medicine, ilam university of medical sciences, ilam, iran m mohebali dept. of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran and center for research of endemic parasites of iran (crepi), tehran university of medical sciences, tehran, iran sh mirhendi dept. of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran mb rokni dept. of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran and center for research of endemic parasites of iran (crepi), tehran university of medical sciences, tehran, iran

background: hydatidosis or cystic hydatid disease is one of the most important diseases in human and animals. identification of strains is important for improvement of control and prevention of dis-ease. the aim of this study was to determine the strains isolated from human and domestic animals in ilam province, iran, using pcr-rflp method. methods: respectively, 30 and 4 animal and human hydat...

2011
Dario Grattapaglia Sergio de Alencar Georgios Pappas

Background The availability of next generation sequencing (NGS) technologies has opened the door to new strategies of SNP discovery and genotyping. Rapid genome-wide SNP detection via deep resequencing of reduced representation libraries of restriction digested pools of genomic DNA combined with a reference genome has been successfully used for SNP discovery in microorganisms [1], plants [2]and...

2015
M. A. Elzo M. G. Thomas D. D. Johnson C. A. Martinez G. C. Lamb D. O. Rae J. G. Wasdin J. D. Driver

Synopsis High rank correlations existed between estimated breeding value for birth weight direct, weaning weight direct, postweaning gain direct, birth weight maternal, and weaning weight maternal from a genomicpolygenic model that used all phenotypic, pedigree, and genotypic information and a polygenic model. Variance components and genetic parameters from these two models were similar for all...

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