نتایج جستجو برای: directed inhibition
تعداد نتایج: 475672 فیلتر نتایج به سال:
A variant of the list method directed forgetting procedure was used to examine the role of inhibition in memory performance following severe closed-head injury (CHI). Twenty-four participants with severe CHI and 24 controls studied picture and word stimuli in both forget and remember conditions. Memory testing for the to-be-forgotten and to-be-remembered items consisted of a free-recall test fo...
Epidermal growth factor receptor (EGFR) and insulin-like growth factor-I receptor (IGF-IR) can cooperate to regulate tumor growth and survival, and synergistic growth inhibition has been reported for combined blockade of EGFR and IGF-IR. However, in preclinical models, only a subset of tumors exhibit high sensitivity to this combination, highlighting the potential need for patient selection to ...
T-cell immunoglobulin and mucin domain 3 (Tim-3) is an immune checkpoint target under investigation in immuno-oncology (IO) trials. Blockade of T-cell-Tim-3 enhances antitumor immunity. Here, we identify additional role for Tim-3 as a growth-suppressive receptor intrinsic to melanoma cells. Inhibition melanoma-Tim-3 by RNA interference promotes, while melanoma-specific overexpression attenuates...
We know that emotion and cognition interact to guide goal-directed behavior. Accordingly, it has recently been shown distracting stimuli (Raymond, Fenske, & Tavassoli, 2003) instructed to-be-forgotten items (Vivas, Marful, Panagiotidou, Bajo, 2016) are emotionally devaluated. The devaluation by inhibition hypothesis is the main theoretical explanation of these effects. However, we little about ...
Rifamycin antibiotics, which inhibit RNA-directed DNA polymerase of Rauscher leuckemia virus, prevent the leukemogenic activity of the virus, and the effect of leukemogenesis correlates with the magnitude of inhibition of the purified enzyme. This inhibition of enzyme activity by rifamycin SV derivatives is due to a relatively tight binding between the enzymes and the inhibitors, yet the bindin...
The regulation of the expression of the Escherichia coli metF gene, which codes for 5,10-methylenetet-rahydrofolate reductase (EC 1.1.99.15), has been investigated by using a simplified DNA-directed in vitro system that measures the formation of the first dipeptide (fMet-Ser) of the gene product. The synthesis of fMet-Ser directed by a plasmid containing the metF gene is specifically inhibited ...
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