BACKGROUND Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by recurrent infections and increased susceptibility to autoimmunity and malignancy. OBJECTIVES This study was performed to estimate the burden of CVID in Iran during 1985-2008 based on incidence, mortality, and disability-adjusted life-years (DALY). METHODS The methods developed by the Wo...

BACKGROUND Mental and substance use disorders are common and often persistent, with many emerging in early life. Compared to adult mental and substance use disorders, the global burden attributable to these disorders in children and youth has received relatively little attention. METHOD Data from the Global Burden of Disease Study 2010 was used to investigate the burden of mental and substanc...

This study is part of a 5-year research project on the national burden of diseases, injuries, and risk factors in Korea. Using disability-adjusted life years (DALYs), a metric introduced by the 1990 Global Burden of Disease (GBD) project, we performed a comprehensive and detailed assessment of the magnitude and distribution of both fatal and non-fatal health problems in the Korean population. T...

Salmonellosis and campylobacteriosis are major foodborne diseases caused by consumption of contaminated raw pork or poultry. Symptomatic disease is mainly characterized by gastroenteritis, although immunoreactive complications also occur, especially among the immunocompromised. Although these diseases cause the highest number of confirmed foodborne bacterial infections in Belgium, their real an...

The WHO Advisory Committee on Health Research (ACHR), through its DALY Review Group, has recently criticized the use of disability-adjusted life years (DALYs). To suggest that the use of DALYs should be discouraged as an aid in health resource allocation may, however, be premature, since it enhances informed debate on the social values that influence resource allocation, identifies health probl...

Abstract Objective: In health economics, one of the important methods of economic evaluation is cost-effectiveness analysis. The usual procedure in this method is to consider effectiveness of Disability-Adjusted Life Years (DALYs) as a measure criterion. Material and Methods: This was a cross sectional study of economic assessment type or Cost-Effectiveness. All over 30 years old population o...

BACKGROUND Health impact assessment (HIA) studies are increasingly predicting the health effects of mode shifts in traffic. The challenge for such studies is to combine the health effects, caused by injuries, with the disease driven health effects, and to express the change in the health with a common health indicator. Disability-adjusted life year (DALY) combines years lived disabled or injure...

BACKGROUND Tick-borne encephalitis (TBE) presents an increasing burden in many parts of Europe, Asian Russia, Siberia, Asian former USSR and Far East. Incidence can be considered as one way to express the burden. A more comprehensive measure concerns disability-adjusted life years (DALYs), better characterizing the full burden of TBE. TBE burden in DALYs has not yet been estimated, nor has it b...

This issue of the Journal features two articles on alcohol. The article 1 by Connor et al details the large health burden from alcohol in New Zealand at an estimated 5.4% of all deaths under 80 years old (around 800 premature deaths annually). They also estimated 6.5% of all healthy life lost among 0–79 year olds in 2004 was attributable to alcohol (a loss of around 28,000 disability-adjusted l...

significant reductions in poverty achieved in recent years. A recent review (Black and others 2008) suggests that maternal and child malnutrition is the underlying cause of 3.5 million deaths annually. Undernutrition accounts for 35 percent of the disease burden in children younger than age 5, and 11 percent of total global disability-adjusted life years (DALYs), a measure that takes into accou...