BACKGROUND To investigate large cup-to-disc ratios (CDR) in children and to determine the relationship between parental CDR and clinical characteristics associated with glaucoma. METHODS Two hundred thirty six children aged 6 to 12 years with CDR ≥ 0.6 were enrolled in this study. Subjects were classified into two groups based on parental CDR: disc suspect children with disc suspect (CDR ≥0.6...

STUDY DESIGN An in vitro biomechanical study using aged human and adolescent porcine discs. OBJECTIVES To find the leakage pathway and effect of needle gauge on the degree of disc injury post anular puncture. SUMMARY OF BACKGROUND DATA Spinal needles are widely used for minimal invasive disc surgeries and disc degeneration/regeneration research. Applications of anular puncture require diffe...

Congenital abnormalities of the optic disc are not so rare. The etiology for the most of them is unknown. Visual acuity of affected eye may be minimally or severely affected, depending on the extent of lesion. All of these conditions can be unilateral or bilateral. Children who have unilateral optic disc abnormalities generally present during the preschool years with sensory esotropia. Visual a...

STUDY DESIGN Measurement and normalization of disc geometry parameters for several animal models used in disc research. OBJECTIVES To compare normalized values of disc geometry to the human disc geometry to aid in the selection and interpretation of animal model studies. SUMMARY OF BACKGROUND DATA Animal models are widely used to study intervertebral disc degeneration and to evaluate disc t...

An interaction between a star-disc system and another star will perturb the disc, possibly resulting in a significant modification of the disc structure and its properties. It is still unclear if such an encounter can trigger fragmentation of the disc to form brown dwarfs or gas giant planets. This paper details high resolution Smoothed Particle Hydrodynamics (SPH) simulations investigating the...

The effects of radial advection and thermal diffusion were considered in investigating the linear stability of an optically thin, two-temperature accretion disc. If the disc has only very little advection, we proved that the thermal instability exists when the disc is geometrically thin. But it dispears in a geometrically slim disc if the thermal diffusion was considered. Moreover, if the disc ...