As orchestrators of essential cellular processes like proliferation, ERK1/2 mitogen-activated protein kinase signals impact on cell cycle regulation. A-type lamins are major constituents of the nuclear matrix that also control the cell cycle machinery by largely unknown mechanisms. In this paper, we disclose a functional liaison between ERK1/2 and lamin A whereby cell cycle progression is regul...

Neotyphodium endophytes are asexual, filamentous fungi, mutualistically associated with diverse cool season grasses. Infected seeds and vegetative organs of infected host plants are the only known modes of propagation of the asexual endophytes. In the last decade certain Epichloë and Neotyphodium-infected grass species have been shown to have epiphyllous structures of the endophytes, hyphae, co...

Placing instrumentation into the ilium has been shown to increase the biomechanical stability and the fusion rates, but it has some disadvantages. The diagonal S2 screw technique is an attractive surgical procedure for degenerative lumbar deformity. Between 2008 and 2010, we carried out long fusion across the lumbosacral junction in 13 patients with a degenerative lumbar deformity using the dia...

OBJECTIVE The purpose of this study was to investigate the importance of environments (dry and wet) to dislodge the clasp. MATERIALS AND METHODS Mandibular test models with natural premolar and molar teeth were used to test four types of clasp (each 12) (Akers, rest plate Akers [RPA], half and half [H-H], and ring clasp) in dry and natural fresh saliva environments. Each clasp was pulled out ...

M.F., a two-year old male, was admitted with severe respiratory distress following accidental inhalation of a peanut. On examination he was semi-conscious, cyanosed and had severe sternal and intercostal retractions associated with a tracheal tug. Several attempts to dislodge the peanut using Heimlich's manoeuvre and back blows were unsuccessful. The child was then brought to the operating thea...

Cochlear implantation may cause a detrimental effect on vestibular function and residual hearing. A significant number of patients with cochlear implant present vertigo. There are several mechanisms for dizziness following implantations. The causes be surgical trauma, disruption normal physiology, or ensuing endolymphatic hydrops. Vibratory trauma affecting the cochlea during cochleostomy plays...

Coffee harvesters utilize vibration systems to dislodge coffee beans. The system is usually coupled the end of an axis (rod cylinder). This cylinder can fail in field, which occurs by means cracks close its flange region that promotes vibration. Numerical simulations are typically used predict strains and stresses based on signals machines general. work acquired strain a harvester rod prototype...

Current treatment for acute ischemic stroke aims at recanalizing the occluded blood vessel to reperfuse brain tissue. Clot removal can be achieved pharmacologically with a thrombolytic drug, such as recombinant tissue plasminogen activator, or mechanical thrombectomy. However, reopening does not guarantee full reperfusion, which has been referred reperfusion failure. When it occurs, failure sig...

This study analyses the role of body size and symmetry in the sexual selection and courtship behavior of Dysdercus maurus Distant. Sexual conflicts signaled by coercive mating, female resistance, and pre-copulation fights illustrate the mating system. Male-female struggles were observed in all mating attempts. Females tried to reject males by pushing or running and even by vigorously shaking th...

I read with interest the technique described in the article by Pang,(1) in which he detailed the common problems with the percutaneous endoscopic gastrostomy (PEG) tube. In our institute, we perform about 450 PEG placements every year. A small percentage of these do dislodge; if this is after the initial track is formed, in our experience, the fastest and easiest way to prevent the stoma from c...