A 43-year-old housewife suffered from an occipital headache, and brain computed tomography (CT) showed an occipital meningeal tumor. She received a complete tumor excision and the tumor pathology was interpreted as atypical meningioma. Five years later, a subacute left neck pain with radiation to the left arm occurred. A tumor invading the second and third cervical vertebrae with compression on...

Peritoneal metastasis from breast cancer is a serious and deadly condition only limited considered in the literature. Our aim was to study prevalence, risk factors, and prognosis of breast cancer peritoneal metastasis. We retrospectively analyzed 3096 women with a diagnosis of invasive breast cancer. We took into consideration presence and localization of breast cancer distant metastasis as wel...

The oral cavity is not a preferred site for metastasis of distant cancers, accounting for only 1% of all oral cancers. Almost all types of cancers can spread to the oral cavity, and usually are late presentation. Sometimes the oral metastasis may manifest as a benign lesion and may cause challenges in its diagnosis. All patients with oral cavity metastasis diagnosed at King Hussein cancer cente...

1 Steven E. Justiniano, Joseph P. McElroy, Lianbo Yu, Ayse Selen Yilmaz, Kevin R. 2 Coombes, Leigha Senter, Rebecca Nagy, Paul Wakely, Jr, Stefano Volinia, Michelle 3 Vinco, Thomas J. Giordano, Carlo M. Croce, Motoyasu Saji, Matthew D. Ringel 4 1 Division of Endocrinology, Diabetes, and Metabolism, Center for Biostatistics and Department 5 of Bioinformatics; Division of Human Genetics, 4 Depart...

Distant metastases are unusual occurrences at presentation and during the progression of epithelial ovarian cancer. There are no good clinical predictors of this phenomenon. Because p53 dysfunction is common in ovarian cancer, we chose to investigate whether specific types of mutations predicted a predisposition to distant metastasis. We hypothesized that the complete absence of intact p53 prot...

Spindle cell carcinoma (SpCC) an aggressive squamous cell carcinoma, variant, frequently metastasizes to regional lymph nodes and distant organs. Unfortunately, an effective treatment method for oral SpCC distant metastasis has not yet been established. Here we present 2 of oral SpCC cases that showed distant metastases after initial treatment, and 2 that showed distant metastases following dur...

In the Czech Republic bone scintigraphy has still been performed routinely as a part of preoperative staging examinations of early breast carcinomas, which had been in 42% diagnosed in the national breast cancer screening program. The incidence of synchronnous distant metastases was analysed for a subgroup of T1N0 breast carcinomas using the database of the Czech National Cancer Registry. Out o...

osteosarcoma may rarely originate from the axial bones such as pelvis or vertebrae. in some pelvic and most vertebral primary tumors, resection often is not possible completely. in general, these tumors cannot be resected with negative margins so they need additional radiotherapy and chemotherapy, but results are unfavourable because of poor local control and high incidence of distant metastase...