In the Indian traditional medicine, Leptadenia pyrotechnica (Apocynaceae) whole plant is claimed to possess powerful diuretic activity. The aim of this study was evaluate potential methanol extract (MELP) in male albino rats. Group I, Control (2% CMC saline solution, 10 ml/kg, b.w), II, serves as a standard drug furosemide (10 mg/kg b.w) and different concentrations LP (100, 200 400 were intrap...