Penggunaan cerium dalam aplikasi sensor telah banyak dikembangkan. Dalam penelitian ini, biosensor elektrokimia dikembangkan untuk mendeteksi DNA mitokondria Sus scrofa menggunakan screen printed carbon elektrode -cerium (SPCE-Ce). Permukaan SPCE sebelum dan sesudah dimodifikasi dengan dikarakterisasi Scanning Electron Microscopy (SEM) voltammetri siklik (CV). Desain urutan nukleotida babi seba...

Mutant TP53 has been demonstrated to be a promising biomarker as it is the most frequently mutated gene in human cancer. However, quantifying mutation presents two unique challenges: broad concentration range and ultralow abundance. This study reports on development of an ultrasensitive highly-selective electrochemical biosensor for rapid detection blood. analysis based network gold-coated magn...

In this paper, single-stranded DNA (ss-DNA) is demonstrated to functionalize graphene (GR) and to further guide the growth of PtAu bimetallic nanoparticles (PtAuNPs) on GR with high densities and dispersion. The obtained nanocomposites (PtAuNPs/ss-DNA/GR) were characterized by transmission electron microscopy (TEM), energy-dispersive X-ray spectrometer (EDS), and electrochemical techniques. The...

Efficient DNA intercalators comprising naphthalene diimide grafted with ethylenedioxythiophene monomer were successfully designed, synthesized and applied to mediate/promote conducting polymer growth electrochemically on biosensor electrodes for direct and amplified DNA detection.

Background: Whispering gallery modes (WGM) biosensors are ultrasensitive systems that can measure amount of adsorbed layer onto the micro-cavity surface. They have many applications including protein, peptide growth, DNA and bacteria detection, molecular properties measurements and specific interaction and drug table recognitions due to their high sensitivity, compact size and label free sensin...

This work describes the development of an integrated biosensor based on phototransistor integrated circuits (IC) for use in medical detection, DNA diagnostics, and gene mapping. The evaluation of various system components developed for an integrated biosensor microchip is discussed. Methods to develop a microarray of DNA probes on nitrocellulose substrate are discussed. The biochip device has s...

The interaction of drugs with DNA is an important aspect in pharmacology. In recent years, many important technological advances have been made to develop new techniques to monitor biorecognition and biointeraction on solid devices. The interaction between DNA and drugs can cause chemical and conformational modifications and, thus, variation of the electrochemical properties of nucleobases. The...

Piezoelectric DNA-based biosensor technology was developed as a new method for detection of M. tuberculosis. This method consists of immobilizing a thiol-modified oligonucleotide probe on the gold electrode surface of a quartz crystal, using a self-assembled monolayer method. The advantage of this study is that a non-amplified genomic bacterial DNA target was used. Instead, the genomic DNA was ...

Artificial DNA motifs as architectural scaffolds have been widely used to assemble a variety of nanoscale devices. Synthetic DNA nanostructures have accomplished mechanical switching in response to external stimuli, suggesting the promise of constructing a walking device that is being used in the field of biosensors. Here, we design a novel miRNA-responsive DNA walker biosensor based on strand ...

Early diagnosis of typhoid is a worldwide concern since the conventional Widal test or Tube agglutination test is questionable for its limitations in terms of delayed implementation and false negative response for detection of Salmonella typhi (the most common food / water borne causative of typhoid) [1-2]. An improved and specific DNA hybridization electrochemical biosensor using direct electr...