Prior to the formal evaluation process, all potential transplant candidates are encouraged to attend a “patient education” session. At the meeting, patients are informed about the medical and surgical risks and benefits of renal transplantation, the necessity for frequent outpatient visits in the early postoperative period, the potential adverse effects of immunosuppression, and the importance ...

Parthenogenetic stem cells (PSCs) are a promising candidate donor for cell therapy applications. Similar to embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), PSCs exhibit self-renewing capacity and clonogenic proliferation in vitro. PSCs exhibit largely haploidentical genotype, and as such may constitute an attractive population for allogenic applications. In this study, P...

We use arguments developed in previous work to identify a second black hole candidate associated with a M31 globular cluster, Bo 144, on the basis of X-ray spectral and timing properties. The 2002 XMM-Newton observation of the associated X-ray source (hereafter XBo 144) revealed behaviour that is common to all low-mass X-ray binaries (LMXBs) in the low-hard state. Studies have shown that neutro...

Many advances in our understanding of the genetic basis of species differences have arisen from transformation experiments, which allow us to study the effect of genes from one species (the donor) when placed in the genetic background of another species (the recipient). Such interspecies transformation experiments are usually focused on candidate genes - genes that, based on work in model syste...

We present evolutionary tracks of binary systems with high mass companion stars and stellar-through-intermediate mass BHs. Using Eggleton’s stellar evolution code, we compute the luminosity produced by accretion from the donor during its entire evolution. We compute also the evolution of the optical spectrum of the binary system taking the disc contribution and irradiation effects into account....

Methods:A candidate was chosen based on strict screening criteria including ongoing immunosuppression, proof of compliance and strong family support. The recipient was an eightyear-old quadrimembral amputee secondary to sepsis with distal forearm amputations who was functional with lower extremity prostheses but had failed upper extremity prostheses. A donor was found with ABO compatibility and...

Adult stem cells are characterised by longer telomeres compared to mature cells from the same tissue. In this study, candidate CD146 (+) umbilical cord (UC) mesenchymal stem cells (MSCs) were purified by cell sorting from UC tissue digests and their telomere lengths were measured in comparison to donor-matched CD146-negative fraction. UC tissue fragments were enzymatically treated with collagen...