BACKGROUND Dorema aucheri is a plant of Apiaceae family which is used widely in some states of Iran. Different extracts and essential oil of Dorema species contain flavonoids and cumarin compounds which have anti-hypertensive, cholesterol- and triglycerides-lowering properties. This study was undertaken to evaluate the genotoxic properties of hydroalcoholic and aqueous extracts of D. aucheri on...

Some Dorema species are used in Persian traditional medicine. In the present study the total extract from the roots of Dorema hyrcanum Koso-Pol. was investigated for its in-vitro (pLDH assay) and in-vivo (Peters' 4-days suppressive test) antiplasmodial effects and assessed for cytotoxicity against the normal cell line MDBK (MTT test). The IC50 values for a chloroquine- sensitive (3D7) and a chl...

most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...