Pancreatic tumors show large interfractional position variation. In addition, changes in gastrointestinal gas volumes and body contour take place over the course of radiation therapy. We aimed to quantify the effect of these anatomical changes on target dose coverage, for the clinically used fiducial marker-based patient position verification and, for comparison, also for simulated bony anatomy...

Background: The purpose of this study was to evaluate the dependency of MAGICA polymer gel dosimeter response (R2) on different electron energies as well as on different mean dose rate for a standard clinically used linear accelerator. Materials and Methods: The sensitivity of the dosimeter was represented by the slope of calibration curve in the linear region measured for each modalit...

Abstract Cancer prevention and treatment are currently the focus of most research. Dose verification is an important step for reducing improper dose deposition during radiotherapy. To mend traditional gel dosimeters 3D verification, a novel rare-earth nanoparticle-based composite was prepared, which has good radioluminescence property reusability. It promising phantom material new dosimeter. TE...

Background: The success of radiation therapy depends on accurate dose delivery to the target. Diode in vivo measurement of entrance and exit dose is a valuable quality assurance (QA) tool to ensure accurate dose delivery.  Materials and Methods: This study was performed at BINO Cancer Hospital, Bahawalpur. Entrance and exit dose measurements were done with p-type diode for various types of canc...

The purpose of this study was to assess the accuracy and efficacy of an automated treatment plan verification, or "secondary check", tool (Mobius3D), which uses a reference dataset to perform an independent three-dimensional dose verification of the treatment planning system (TPS) dose calculation and assesses plan quality by comparing dose-volume histograms to reference benchmarks. The accurac...

Background: Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like developed to date. Among the special features of this type of dosimeters, is be doped with other elements or chemicals which made them appropriate for investigating of dose enhancement with contrast agents, by high atomic number. Material and Methods: In this study...

The potential for medication error is great with chemotherapy agents because of their high toxicity profile, small therapeutic index, and numerous dose-limiting adverse effects. The oncology team involved with chemotherapy treatment planning and administration assumes an active role in preventing such events by obtaining and maintaining competency in dose calculations, having knowledge of dose-...

One of the most important aspects of quality assurance (QA) in radiation therapy is redundancy of patient treatment dose calculation. This work is focused on the patient-specific time and 3D dose treatment plan verification for stereotactic radiosurgery using Leksell Gamma Knife Perfexion (LGK PFX). The virtual model of LGK PFX was developed in MATLAB, based on the physical dimensions provided ...