A randomised controlled multicentre trial was performed in 160 patients with gastric ulcer, proved by endoscopy and biopsy, to compare ulcer healing with sucralfate and ranitidine (double blind double dummy design) and to assess the effect of maintenance treatment with sucralfate on ulcer recurrence (double blind placebo controlled design). The healing rates were similar with 4 g sucralfate sus...

BACKGROUND/AIMS Studies evaluating the human pylorus as a sphincter are scanty and contradictory. Recently, we have shown technical feasibility of transposing the human pylorus for end-stage fecal incontinence. This unique cohort of patients provided us an opportunity to study the sphincter properties of the pylorus in its ectopic position. METHODS Antro-pylorus transposition on end sigmoid c...

The effects of intragastric infusion of 10% Intralipid and 10% dextrose on the intraluminal pressures in the antrum, pylorus and duodenal bulb have been examined. Ten studies with each infusate have been performed in 10 normal subjects and the results compared with those obtained previously in 22 studies during intragastric infusion of isotonic saline. During saline infusion, contractile activi...

OBJECTIVE Gastroparesis is a disorder of delayed gastric emptying that is often chronic in nature. Up to 50% of type 1 diabetic subjects have symptoms of gastroparesis, which include nausea, vomiting, and early satiety. Elevated pyloric pressures may be responsible for delayed gastric emptying in diabetic subjects. Botulinum toxin inhibits the release of acetylcholine and produces transient par...

a 4-year-old female native goat with the history of inappetence and no defecation was referred to the department of clinical sciences, school of veterinary medicine of shiraz, shiraz, southern iran. during exploratory laparotomy, pyloric obstruction and displacement of the abomasum to the left side was observed. obstruction of pylorus was due to a ball-shaped phytobezoar. the goat was followed ...

The function of the pylorus and the pyloric antrum in the control of gastric emptying has been studied in an isolated rat stomach-duodenum preparation. Pressures in the body and pyloric antrum and flow through the duodenum were recorded using electronic transducers. Vigorous peristalsis and episodic flow were induced by electrical stimulation. The pylorus is normally open until it is transientl...