The correlation between gap junction morphology and the state of electrical coupling was investigated in the frog auricle, which presents an atypical gap-junction organization. Electrical uncoupling of the tissue was achieved by perfusion with CO2-saturated Ringer medium. The tissue was fixed with glutaraldehyde and freeze-fractured before and during the application of CO2-saturated Ringer medi...

Zusammenfassung: Das DSG 2000 enthält, wie schon das DSG 1978 eine Verpflichtung zur Ergreifung von Datensicherheitsmaßnahmen. Neben den bisherigen Maßnahmen, die etwa Zutrittsund Zugriffsbeschränkungen umfassen, wurde eine neue Protokollierungspflicht eingeführt. Dieser Beitrag setzt sich mit den Datensicherheitsmaßnahmen im allgemeinen und insbesondere mit den Fragen rund um die neue Protokol...

Immunotoxins are potent cell-killing agents that may be useful in the treatment of cancer. The early production of neutralizing antibodies to immunotoxins is one of the major limiting factors for their use in humans. 15-Deoxyspergualin (DSG), a derivative of spergualin, which is a metabolite of Bacillus laterosporus, has been found to have immunosuppressive activity in rodents, dogs, and primat...

Based on a thorough review of the available literature in the delayed-onset muscle soreness (DOMS) model, we identified multiple study design characteristics that are considered to be normative in acute pain research but have not been followed in a majority of published DOMS experiments. We designed an analgesic investigation using the DOMS model that both complied with current scientifically a...

With the development of industry and the improvement of living standards, better quality in power electric service is required more than ever before. This paper deals with the optimal algorithms for voltage regulation in the case where Distributed Storage and Generation (DSG) systems are operated in distribution systems. It is very difficult to handle the interconnection issues for proper volta...

We have used the newly engineered transposable element Dsg to tag a gene that gives rise to a defective kernel (dek) phenotype. Dsg requires the autonomous element Ac for transposition. Upon excision, it leaves a short DNA footprint that can create in-frame and frameshift insertions in coding sequences. Therefore, we could create alleles of the tagged gene that confirmed causation of the dek ph...

Abstract Spiral arms serve crucial purposes in star formation and galaxy evolution. In this paper, we report the identification of “A2744-DSG- z 3,” a dusty, multiarm spiral at = 3.059 using James Webb Space Telescope (JWST) NIRISS imaging grism spectroscopy. A2744-DSG-z3 was discovered as gravitationally lensed submillimeter with Atacama Large Millimeter/submillimeter Array (ALMA). This is mos...

We studied the kink-antikink collision process for the "double sine-Gordon" (DSG) equation in 1+1 dimensions at different values of the potential parameter R>0. For small values of R we discuss the problem of resonance frequencies. We give qualitative explanation of the frequency shift in comparison with the frequency of the discrete level in the potential well of isolated kink. We show that in...

A new antibiotic, deoxyspergualin (DSG), demonstrated antitumor activity against L1210 leukemia in mice. The life span of mice bearing either i.p. or s.c.-implanted L1210 increased greater than 150% following i.p. administration of 25 mg/kg DSG on days 1-9. Activity obtained with i.p. bolus treatments was schedule dependent. The tumor burden in mice bearing the s.c. implanted L1210 was reduced ...

BACKGROUND Topical diclofenac sodium 1% gel (DSG) has demonstrated efficacy and tolerability in patients with osteoarthritis (OA) of the knees or hands, including elderly patients and those with an increased risk of gastrointestinal, cardiovascular, and renal adverse events (AEs). Medications known to interact with diclofenac were disallowed in a clinical trial of DSG for knee OA; however, pati...