flavonoids polyphenolic compounds that exert many anti-inflammatory and anti-microbial effects, and exhibit an anti-allergic action. quercetin is a flavonoids that recently  has  raised  many  issues  and  shown  evidence about its action as a potential drug to allergy. a chinese herbal formula, known as food allergy herbal formula (fahf) has been related with blocking of anaphylaxis to peanuts...

BACKGROUND Previous epidemiologic studies have reported that a history of allergy is associated with reduced risk of colorectal cancer and other malignancies. However, no information is available for the association between allergy and the risk of lymph node metastasis. Our study was designed to determine this association in rectal cancer. METHODS Patients who were treated at our hospital in ...

General considerations on rapid desensitization for drug hypersensitivity – a consensus statement J. R. Cernadas* , K. Brockow* , A. Romano* , W. Aberer , M. J. Torres , A. Bircher , P. Campi , M. L. Sanz , M. Castells, P. Demoly & W. J. Pichler , for the European Network of Drug Allergy and the EAACI interest group on drug hypersensitivity Department of Allergy and Clinical Immunology, Medical...

National Institute for Health and Care Excellence (NICE) guidelines state that all healthcare organisations should put policies in place for medication reconciliation on admission. At Croydon University Hospital a medication history had previously been taken in Foundation Year 1 (FY1) preoperative clinics. However, when these clinics were deemed unnecessary, this opportunity for drug chart docu...

Acute myocardial infarction (AMI) is one of the main leading causes of mortality and morbidity. Despite the progress in the treatment of AMI, streptokinase is still being used in many countries. Because of the critical condition of patients with AMI and complications of streptokinase therapy, this study was performed to evaluate the pattern of adverse drug reaction (ADRs) induced by streptokina...

Evidence is accumulating that supports a role for acute desensitization for IgE-mediated drug allergy in those patients for whom no alternative drug exists. While most of the studies have been performed in penicillin-allergic patients, this procedure has been used safely in patients with IgE sensitivity to other agents. In addition, it has been shown that modified desensitization protocols may ...

Introduction: Drug induced allergy or hypersensitivity reaction is of great clinical significance in therapeutics. Various factors may contribute like age, genetic composition, disease of the patients and the types of drugs used. Such reactions increases the patient’s suffering and lowers the therapeutic efficacy of any drug. Therefore, it is essential to collect data and investigate important ...

Since the discovery of the anaesthetic effect of cocaine in 1884, local anaesthetics (LAs) have been widely used. It has been estimated that 6 million people are injected with LAs each day around the world. In spite of their widespread use, true hypersensitivity appears to be infrequent. However the perception of allergy to LA among the general public is high. In our drug allergy clinic, referr...