background: nosocomial infections are an important cause of hospital mortalities. staphylococcus aureus (s. aureus) carriers among medical staff are an important source of nosocomial infections. the purpose of this study was to investigate the prevalence of the nasal carriers of s. aureus and antibiotic resistance in staff of nikuee hospital, qom, iran. materials and methods: in this cross-sect...

drug resistance (especially multiple drug resistance) in mycobacterium tuberculosis makes global concerns in treatment and control of tuberculosis. rapid diagnosis of drug resistant strains of the bacteria has vital importance in the prognosis of the disease. the aim of this study was to identify the mutations responsible for drug resistance in mycobacterium tuberculosis strains derived from pa...

conclusions all the staphylococcus aureus strains and enterococcus faecium strains were sensitive to members of the oxazolidinone class of linezolid drug. development of multi drug resistance by gram positive bacteria constitutes a very serious challenge for medical practice. despite these rising rates, it is impossible to distinguish where they have originated from and special attention has th...

antimicrobial peptides (amps) are extensive group of molecules that produced by variety tissues of invertebrate, plants, and animal species which play an important role in their immunity response. amps have different classifications such as; biosynthetic machines, biological sources, biological functions, molecular properties, covalent bonding patterns, three dimensional structures, and molecul...

introduction: many people are used medicinal plants due to natural, low risks and complications, and low costs as compared with the synthetic drugs. incidence of drug resistance against chemical antimicrobial drugs has led the use of medicinal plants for treatment of infections in recent years. the aim of this study was to examine possible antibacterial effects of four herbal plants in vitro.  ...

b ackground : acinetobacter baumannii , is an important opportunistic pathogens   responsible   for   nosocomial   infections.   the   aim   of   this experiment  was  to  determine  prevalence  of  class  i  integron  in   a. baumannii strains isolated from burn patients in mottahari hospital and the drug susceptibility pattern. methods : there were 69 acinetobacter isolates, 68 (98.5%) were i...

background acinetobacter has become an important cause of different infections such as wound infection, due to its great ability to survive and spread in hospital settings and to develop resistance against many antibiotics. objectives the aim of this study was to investigate the antibiotic resistance among isolates of acinetobacter from wound infections during a 7-year period, from 2005 to 2011...

background: staphylococcus aureus is a major human pathogen. due to high prevalence of s. aureus infections and increasing resistance to antibiotics, physicians have been facing problems in choosing the appropriate empirical antibiotic therapy for such infections. objectives: the aim of this study was to determine the pattern of antibiotic resistance in s. aureus clinical isolates of mashhad qu...

background: one of the limitations in the treatment of common diseases such as cancer chemotherapy is development of multidrug re sistance (mdr). polymorphisms could alter the expression level of mdr1 gene, which plays an important role in mdr. in this research, the frequency of c3435t, c1236t, and g2677t/a polymorphisms of mdr1 gene was investigated in a large group of population from hamadan ...