introduction: intravenous general anesthetic agents are among the most important and widely used anesthetic drugs in the clinical practice. many pharmacological studies have shown that potentiation of gaba and glycine on their receptors is the most plausible mechanism. nevertheless, there is limited information on the effects of co-administration of two or more of these agents. however, experim...

tuberculosis of the foot is an uncommon entity and the reported incidence is 0.1% to 0.3%. the isolated tuberculosis of talonavicular joint is exceptionally rare. in tuberculosis of the foot and ankle, the presentation is usually nonspecific. the diagnosis of tuberculosis affecting foot is difficult, especially when it is isolated. in doubtful cases, diagnosis should be confirmed by histopathol...

background: glybenclamide and metformin are two of the most common oral hypoglycemic drugs which are often used in treatment of type ii diabetes mellitus. toxicity due to these drugs may occur intentionally, accidentally, or even at the normal dosage because of the progression of such internal diseases as renal dysfunction. methods: in this case series study, 59 patients poisoned with oral hypo...

introduction: regarding the high rate of depression in our society, using anti-depressive drugs especially tricycle antidepressants (tcas) is increasing and poisoning by these agents has become more common than other drugs. due to its incident and dire complications we decided to study the treatment quality in poisoned patients with tcass admitted in emergency ward of arak,s vali-e-asr hospital...

how to cite this article: karimzadeh p, bakrani v. antiepileptic drug-related adverse reactions and factors influencing these reactions. iran j child neurol. 2013 summer; 7(3):23-27.   objective according to the basic role of drug side effects in selection of an appropriate drug, patient compliance and the quality of life in epileptic patients, and forasmuch as new dugs with unknown side effect...

background drug dependence is one of the major problems in today’s world which has turned into a serious, concerning threat due to its destructive and preventive effects on the development and prosperity of the society. objectives the study aimed to investigate the effectiveness of social skills training on tendency to addiction among high school female students of ahvaz city. patients and meth...

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OBJECTIVE To characterize the types of comparators and endpoints used in efficacy trials for approvals of supplemental indications, compared with the data supporting these drugs' originally approved indications. DESIGN Systematic review. SETTING Publicly accessible data on supplemental indications approved by the US Food and Drug Administration from 2005 to 2014. MAIN OUTCOME MEASURES Typ...

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