Bone marrow fibrosis leading to dry tap aspiration and often associated with blast crisis has previously been reported in both Chronic myeloid leukemia Primary myelofibrosis. The similarities between these two conditions terms of clinical presentation morphology can really create a diagnostic dilemma. Here we present case 32 year old lady which closely resembled myelofibrosis transformation. Al...

We present circuits and techniques which allow the extraction of fine-grained timing information using a simple, scan-based, test-access port such as the JTAG/IEEE 1149 standard. We go on to show how these techniques can be combined with other simple circuits for post-fabrication timing control. These techniques open up opportunities to perform timing oriented tests through TAP control. Further...

Intensive vegetation management alters seedling growth and development in southcm pine plantations. Adequate light, moisture. and nutrients stimulate seedling stem growth and crown development. Thus rapid stem growth could deplete nutrient and energy resources required for aggressive rcot growth. Early root system expansion within the available rooting zone is critical because structural root g...

BACKGROUND Prevalence of exercise-induced bronchoconstriction (EIB) is high in elite athletes, especially after many years training in cold and dry air conditions. The primary treatment of EIB is inhaling a short-acting beta-2-agonist such as salbutamol. However, professional speed skaters also inhale nebulized isotonic saline or tap water before and after a race or intense training. The use of...

This study provides, for the first time, an evaluation of the physicochemical properties of batch cooling crystallized mannitol particles combined with how these properties correlated with the inhalation performance from a dry powder inhaler (Aerolizer). The results showed that the type of polymorph changed from β-form (commercial mannitol) to mixtures of β+ δ-mannitol (cooling crystallized man...