The proposed influence of cosmic rays on cloud formation is tested for the effect of sudden intensity changes of CR (Forbush decreases) on cloudiness. An attempt is made to widen the investigated period covered by satellite observation of cloudiness. As an indicator of cloud cover, the diurnal temperature range (DTR a quantity anticorrelated with cloudiness) is used. The superposed epoch analys...

Alveolar macrophages play a critical role in initiating the immune response to inhaled pathogens and have been shown to be the first cell type infected following intranasal inoculation with several pathogens, including Francisella tularensis. In an attempt to further dissect the role of alveolar macrophages in the immune response to Francisella, we selectively depleted alveolar macrophages usin...

Monocyte/macrophage recruitment correlates strongly with the progression of renal impairment in diabetic nephropathy (DN), yet their direct role is not clear. We hypothesized that macrophages contribute to direct podocyte injury and/or an abnormal podocyte niche leading to DN. Experiments were conducted in CD11b-DTR mice treated with diphtheria toxin (DT) to deplete macrophages after streptozot...

Several studies suggest the potential for climate change to increase malaria incidence in cooler, marginal transmission environments. However, the effect of increasing temperature in warmer regions where conditions currently support endemic transmission has received less attention. We investigate how increases in temperature from optimal conditions (27 °C to 30 °C and 33 °C) interact with reali...

To precisely evaluate low back pain, identification of the detailed innervation of the lumbar spine is necessary. On twenty-five sides of adult cadavers we investigated various patterns of rami communicantes (RC) and their relationship to the psoas major muscle (PM). In ten sides, we focused our dissection on the minute nerve supply of the anterior (ALL) and posterior longitudinal ligaments (PL...

Most U.S. healthcare professionals encourage mutual-help group involvement as an adjunct to treatment or aftercare for individuals with substance use disorders, yet there are multiple challenges in engaging in these community groups. Dually diagnosed individuals (DDIs) may face additional challenges in affiliating with mutual-help groups. Twelve-step facilitation for DDIs (TSF-DD), a manualized...

introduction: air temperature as an important climatic factor can influence variability and distribution of other climatic parameters. therefore, tracking the changes in air temperature is a popular procedure in climate change studies.. according to the national academy in the last decade, global temperature has raised 0.4 to 0.8⁰c. instrumental records show that, with the exception of 1998, th...

ABSTRACT Most previous studies of extreme temperatures have primarily focused on atmospheric temperatures. Using 18 years the latest version Moderate Resolution Imaging Spectroradiometer (MODIS) land surface temperature (LST) data, we globally investigate spatial patterns hot and cold extremes as well diurnal range (DTR). We show that world’s highest LST 80.8°C, observed in Lut Desert Iran Sono...

The Karnali River Basin (KRB) comprises the longest river in Nepal, located south of Himalayas. Despite its high susceptibility to floods, basin lacks detailed studies. Proper floodplain management is essential reduce impacts due rising flood frequency, magnitude, and severity aggravated by climate change. This research applies three machine learning techniques, Support Vector Machine (SVM), Ra...

[Purpose] The aim of this study was to investigate the clinical usefulness of a novel apparatus intended to improve the consistency and reliability of the deep tendon reflex (DTR) test. [Subjects] The participants included 50 healthy adults (25 male and 25 female) between 20 and 31 years of age who showed no knee abnormalities upon physical examination. [Methods] The intraclass correlation coef...