نتایج جستجو برای: dubin
تعداد نتایج: 268 فیلتر نتایج به سال:
Recently our knowledge of bilirubin metabolism has increased considerably. Perhaps the most stimulating discovery has been that bilirubin is excreted in the bile as a glucuronide (Billing, Cole and Lathe, 1957; Schmid, 1957). This has made it possible to classify some rare types of chronic jaundice more definitely. One of these, chronic non-haemolytic familial jaundice, was described many years...
Les auteurs presentent quatre cas familiaux de l'ictcre chronique, non hemolytique, benin, avec une hyperbilirubinemie a predominance conjuguee. Deux malades ont ete soumis a des investigations plus poussees. Les. voies biliaires etaient visib1es a la cholecystographie ora1e et le taux plasmatique de la BSP, elevc au depart, presentait une pente d'elimination progressive sans remontee secondai...
Dubin-Johnson syndrome (DJS) is a benign autosomal recessive liver disorder characterised by an intermittent jaundice caused by chronic and conjugated hyperbilirubinaemia. Many mutations in multidrug resistance associated protein (MRP-2) gene have been identified in patients with DJS. Although the disease is usually asymptomatic, some patients may experience vague abdominal pain. In this report...
Cholestasis may be defined as stagnation of bile within the intrahepatic or extrahepatic biliary tree. Biochemically, there is retention of conjugated bilirubin, bile salts, and alkaline phosphatase; morphologically, there is at least dilatation of biliary canaliculi and loss of their microvilli, and later accumulation of bile pigment in the canaliculi (bile plugs)."0 The mechanism underlying t...
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