Approximately, 10 to 20% of patients with peptic ulcer suffer a perforation of stomach or duodenum in which chemical peritonitis develop initially from gastric and duodenal secretion but in a few hours bacterial contamination superimpose the disease. The disease could be life-threatening, early diagnosis and treatment is extremely important. The mortality will increase up if perforation exists ...

Endoscopic submucosal dissection (ESD) has gained popularity since it was first reported in Japan, and in recent years this modality has spread throughout the world. En bloc specimens that are resected by ESD contribute to accurate to the performance of pathological examinations upon which a patient’s treatment and prognosis relies (1). Primary duodenal adenoma and cancer are reported to accoun...

BACKGROUND Its a dilemma to attempt a palliative procedure to debulk the tumour and/or prevent future obstructive complications in a locally advanced intra abdominal malignancy. CASE PRESENTATION A 38 year old Vietnamese man presented with a carcinoma of the colon which had invaded the gallbladder and duodenum with a sealed perforation of the second part of the duodenum. Following surgical ex...

Plasmodium falciparum, the commonest cause of severe malaria in children, is an important cause of mortality in developing nations like Nepal. Duodenal perforation in a case of complicated malaria, although a rare entity, can occur in children. Early diagnosis, proper medical treatment, and early surgical repair can be a lifesaving measure in such cases. Here, we report a case of a 5-year-old m...

A 40-year-old man, with no significant history of past illness, presented to our emergency department with classic features of perforation peritonitis. Exploratory laparotomy showed duodenal perforation, which was closed with an omental patch. Before suturing the perforation, however, a nasojejunal tube was inserted for feeding. The postoperative period was uneventful and the patient was allowe...

BACKGROUND The most common complications of peptic ulcer are bleeding and perforation. In many regions, definitive acid reduction surgery has given way to simple closure and Helicobacter pylori eradication. AIM To perform a systematic review and meta-analysis to ask whether this change in practice is in fact justified. MATERIALS AND METHODS A search on the Cochrane Controlled Trials Registe...