• Objective: To assess the impact of a drug utilization review (DUR) alert letter program on metformin discontinuation rates in patients with a metformin claim and an absolute contraindication to metformin

Grant Agreement nr 611057 Project acronym EUMSSI Start date of project (dur.) December 1st 2013 (36 months) Document due Date : 31 May 2014 Actual date of delivery 6 June 2014 Leader LUH Reply to [email protected] Document status Submitted

A math e mat i cal model rep re sent ing tem per a ture and mois ture con tent in bread dur ing bak ing is de vel oped. The model em ploys the cou pled par tial dif fer en tial equa tions pro posed by Luikov. Dependences of mass and ther mal prop er ties of dough on tem per a ture and mois ture con tent are in cluded in the model. Re sult ing sys tem of non-lin ear par tial dif fer en tial equa...

Bi r th weight is in large extent influenced by gestational age. In addi tion genetic and envi ronmental factors determine intrauter ine growth and bi r th weight. The contr ibutions of these factors may be influenced by maternal smoking dur ing pregnancy. We examined bi r th weight and maternal smoking in a sample of 2930 twin pai rs from the Nether lands Twin Register using structural equatio...

Athletes with spinal cord injury (SCI), and in particular tetraplegia, have an increased risk of heat strain and consequently heat illness relative to able-bodied individuals. Strategies that reduce the heat strain during exercise in a hot environment may reduce the risk of heat illness. To test the hypotheses that precooling or cooling during intermittent sprint exercise in a heated environmen...

The medical and societal consequences of the misuse pharmaceuticals clearly justify need for comprehensive drug utilization research (DUR). Wastewater-based epidemiology (WBE) employs analysis human metabolic excretion products in wastewater to monitor consumption patterns xenobiotics at population level. Recently, WBE has demonstrated its potential evaluate lifestyle factors such as illicit dr...