نتایج جستجو برای: early onset breast cancer

تعداد نتایج: 1725716  

Journal: :Technology in Cancer Research & Treatment 2020

2013
Rosanna Upstill-Goddard Diana Eccles Sarah Ennis Sajjad Rafiq William Tapper Joerg Fliege Andrew Collins

Two major breast cancer sub-types are defined by the expression of estrogen receptors on tumour cells. Cancers with large numbers of receptors are termed estrogen receptor positive and those with few are estrogen receptor negative. Using genome-wide single nucleotide polymorphism genotype data for a sample of early-onset breast cancer patients we developed a Support Vector Machine (SVM) classif...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Sharon Cantor Ronny Drapkin Fan Zhang Yafang Lin Juliana Han Sushmita Pamidi David M Livingston

BACH1 is a nuclear protein that directly interacts with the highly conserved, C-terminal BRCT repeats of the tumor suppressor, BRCA1. Mutations within the BRCT repeats disrupt the interaction between BRCA1 and BACH1, lead to defects in DNA repair, and result in breast and ovarian cancer. BACH1 is necessary for efficient double-strand break repair in a manner that depends on its association with...

روشنایی, قدرت اله, صدیقی پاشاکی, عبدالعظیم, فردمال, جواد, مافی, مریم, کرمی, منوچهر,

Background and Objective: Breast cancer is the most common cancer among women. Various factors are associated with survival of patients with breast cancer. The aim of this study was to determine the survival rate of patients with breast cancer who referred to MRI center of Hamadan and to explore its related factors. Materials and Methods: In this historical cohort study, 542 women with breast c...

Journal: :Journal of medical genetics 2005
S-W Kim C S Lee J V Fey P I Borgen J Boyd

E pidemiological data suggest that 7% of breast cancer cases and 10% of ovarian cancer cases in the general population are attributable to one or more autosomal dominant susceptibility alleles. The breast and ovarian cancer susceptibility genes BRCA1 and BRCA2 were isolated in 1994 and 1995, 4 respectively, and since then, a large volume of literature attests to the involvement of these genes i...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید