we conducted this study to determine the level of immunity after vaccination of lambs with whole bodyechinococcus granulosus. to do so, 200 mature e. granulosus parasites, which were kept in 10% formalinefor 8 months, were obtained from the department of parasitology, school of veterinary medicine, ferdowsiuniversity of mashhad. the soluble protein of the parasite was prepared. the sample was h...

background: cystic echinococcosis (ce), also known as echinococcosis/hydatidosis, is one of the most important parasitic diseases in the world. it enhances both humoral and cellular (th1 and th2) responses in infected host. different antigens of the worm may favor the th1 or th2 immune responses in ce patients. objective: to evaluate the humoral and cellular immune responses of balb/c mice agai...

conclusions based on this report (of a patient presented with an intramedullary cyst in the long bones), the primary bone hydatid cyst disease should be kept in mind and be investigated in the differential diagnosis. case presentations in this study, an evaluation was made of a patient referred at yozgat state hospital orthopedics and traumatology polyclinic with complaints of pain in her left ...

Echinococcus granulosus exhibits substantial genetic diversity that has important implications for the design and development of vaccines, diagnostic reagents and drugs effective against this parasite. DNA approaches that have been used for accurate identification of these genetic variants are presented here as is a description of their application in molecular epidemiological surveys of cystic...

In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led ...

background : echinococcosis or hydatidosis is a chronic, zoonotic worldwide infection caused by the larval stage of the dog taeniid tapeworm echinococcus granulosus. vaccination has been considered as one of the ways to prevent of hy-datidosis in recent decades. the aim of this study was to construct a pcdna3.1 eukaryotic expression vector contain-ing the subunit 8-kda antigen b (hyd1) of e. gr...

The Echinococcus Western Blot IgG (LDBIO Diagnostics, Lyon, France), using a whole larval antigen from Echinococcus multilocularis, was evaluated for serodiagnosis and differentiation between two human parasitic infections of worldwide importance: cystic echinococcosis, due to Echinococcus granulosus, and alveolar echinococcosis, due to E. multilocularis. Fifty and 61 serum samples from patient...

In the eastern Tibetan plateau both human cystic and alveolar echinococcosis (AE) caused by infection with Echincoccus granulosus or Echinococcus multilocularis, respectively are highly endemic. The domestic dog plays a key role in zoonotic transmission in this region. Our primary objective was to investigate the role of domestic dogs in maintaining transmission of E. multilocularis in Shiqu co...