Marfan syndrome, homocystinuria, trauma, and simple ectopia lentis are the most common causes of pediatric lens subluxation. Many patients are best treated with a careful refraction of the phakic or aphakic pupillary axis. For those patients not achieving satisfactory refractive results, endocapsular lensectomy using modern automated vitreous cutting devices is relatively safe and successful. G...

CORECTOPIA is usually bilateral and symmetrical, the direction of the displacement being up and out (Duke-Elder, 1938). Unilateral cases are rare (Wilde, 1862; van Duyse, 1895). Ectopia lentis is a usual accompaniment, and other anomalies of uveal tissue may co-exist. This condition has a hereditary tendency as a recessive characteristic. Some of the cases reported have shown evidence of intra-...

OBJECTIVE To assess the causes for delay in the diagnosis of homocystinuria. DESIGN Clinical and laboratory data were collected from patients diagnosed as having homocystinuria due to cystathionine synthase deficiency, with special reference to the ages at which the patients had their first major signs of the disease, ectopia lentis was established, and homocystinuria was diagnosed. SETTING...

FAMILIAL ectopia lentis is a well recognized condition and is usually seen by the ophthalmologist in its fully developed stage. It was thought worth while to record this family, as some of the very earliest stages have been observed and the complications of the condition have been very varied. The family is a large one, spread over a large part of the Union of South Africa, and it has not been ...

The clinical features of pigmented lens striae were studied biomicroscopically in seven patients. The lenses of three of these, obtained by cataract surgery, were examined by electron microscopy to determine the structure of the striae. We concluded that the striae are not formed by remnants of tunica vasculosa lentis, as earlier workers believed, but consist of fine fibrils of zonular bundles ...