an important issue in implementation of a gis system is preparation of data to be entered in gis. to produce spatial data for gis using photogrammetric techniques, conventional method is to apply photogrammetric and gis systems individually (off-line procedure). this approach is costly, time consuming and somehow unreliable due to the fact that 3d photogrammetric model is not available at the t...

Genome editing (GE) is one of the most efficient and useful molecular approaches to correct effects gene mutations in hereditary monogenetic diseases, including β-thalassemia. CRISPR-Cas9 has been proposed for effective correction β-thalassemia mutation, obtaining high-level “ de novo ” production adult hemoglobin (HbA). In addition primary causing β-thalassemia, several reports demonstrate tha...

Bioinformatic software has used various numerical encoding schemes to describe amino acid sequences. Orthogonal encoding, employing 20 numbers to describe the amino acid type of one protein residue, is often used with artificial neural network (ANN) models. However, this can increase the model complexity, thus leading to difficulty in implementation and poor performance. Here, we use ANNs to de...

Longitudinal Relaxation Time Editing for Acetylcarnitine Detection with H-MRS, Lucas Lindeboom, Yvonne M.H. Bruls, Petronella A. van Ewijk, Matthijs K.C. Hesselink, Joachim E. Wildberger, Patrick Schrauwen, and Vera B. Schrauwen-Hinderling ......................... 505 Published online 17 February 2016 Efficient Spectroscopic Imaging by an Optimized Encoding of Pretargeted Resonances, Zhiyong Z...

This paper discusses how using the 10-bit 4:2:2 AVC/H.264 encoding profile for transmission can maintain quality throughout the production process workflow. Upto now an MPEG-2 4:2:2 8-bit profile was used, the new AVC/H.264 encoding profile will allow for significantly lower transmission bandwidth or higher quality for the same transmission links. The profile is also compatible with pre-existin...

The most highly conserved structures of group II introns are the helical domains V and VI near the 3'splice site. Within this region of each of the four introns in the wheat mitochondrial nad7 gene encoding NADH dehydrogenase subunit 7, there are A-C mispairs. To determine whether C-to-U type RNA editing restores conventional A-U pairing, we sequenced RT-PCR products from partially-spliced nad7...

Apolipoprotein B (apoB) mRNA editing involves site-specific deamination of cytidine to form uridine, resulting in the production of an in-frame stop codon. Protein translated from edited mRNA is associated with a reduced risk of atherosclerosis, and hence the protein factors that regulate hepatic apoB mRNA editing are of interest. A human protein essential for apoB mRNA editing and an eight-ami...

The nucleotide sequence of the phosphoprotein (P) gene of a dolphin morbillivirus (DMV) isolate was determined. Like those of other morbilliviruses the DMV P gene encoded P and C proteins in overlapping open reading frames and V protein by editing the P gene transcript. Among P mRNA based clones the editing site variants GGGC, GGGG, GAGC and GGGGGGC predicting a P protein, and the variants GGGG...