Wenjie Gong, Guangming Xiong, Edmund Maser* 5 6 Institute of Toxicology and Pharmacology for Natural Scientists, University Medical School, Schleswig7 Holstein, Campus Kiel, Brunswiker Strasse 10,D-24105 Kiel, Germany 8 9 *Corresponding author: Prof. Edmund Maser, Tel.: +49-431-597-3540; fax: +49-431-597-3558; 10 E-mail address: [email protected] (E. Maser) 11 12 Running Title: HsdR positi...