background: expansion of gaa trinucleotide repeats is the molecular basis of friedreich’s ataxia (frda). precise detection of the gaa expansion repeat in frataxin gene has always been a challenge. different molecular methods have been suggested for detection of gaa expansion, including; short-pcr, long-pcr, triplet repeat primed-pcr (tp-pcr) and southern blotting. the aim of study was to evalua...

RATIONALE, AIMS AND OBJECTIVES Reducing preventable harm from repeat medication prescriptions is a patient safety priority worldwide. In the United Kingdom, repeat prescriptions items issued has doubled in the last 20 years from 5.8 to 13.3 items per patient per annum. This has significant resource implications and consequences for avoidable patient harms. Consequently, we aimed to test a risk ...

POSTPARTUM CONTRACEPTION AND RAPID REPEAT PREGNANCIES IN RURAL, LOW-INCOME BLACK WOMEN WITH BASELINE RISK FACTOR COMPARISONS By KAREN LI July 27, 2015 INTRODUCTION: The residents in the Low Country region of South Carolina consist of a predominantly low-income, African American population with a history of trauma and experiences of racism. Chronic conditions, unintended pregnancies, and adverse...

OBJECTIVE To assess the knowledge, attitudes and practices regarding sexuality, high risk sexual behaviors and methods of contraception, among college/university students of Karachi, Pakistan. STUDY DESIGN Cross-sectional observational study. PLACE AND DURATION OF STUDY Higher Education Commission-recognized government and private colleges/universities in Karachi from 2005-2006. METHODOLO...

introduction: the examination of radiographics repeat rate and the causes are considered as one of the main factors in assessing the performance of radiographers and the function of the equipments in radiography services. the analysis of repeated films can reveal sources of the errors and areas where improvement can be made. apart from imposing additional charges, the repeats are responsible fo...

for repeat testing. The authors’ conclusion that it should be considered for screening patients requires further consideration and study but conceivably, this assay should improve the future of VWD diagnosis. Conflict-of-interest disclosure: P.D.J. has received research funding from Bayer, CSL Behring, and Octapharma; and honoraria for educational talks from Baxalta, CSL Behring, and Octapharma. n

Background & Aims: Nearly 30 hereditary disorders in humans result from an increase in the number of copies of simple repeats in genomic DNA, including fragile X syndrome, myotonic dystrophy, Huntington’s disease, and Friedreich’s ataxia. One the most frequently occurring types of mutation is trinucleotide repeat expansion. The present study was conducted with the aim of investigating the cause...