Cross-protection against non-HPV16/18 types and the emergence of broad spectrum vaccines protecting against multiple HPV types will influence the cost-effectiveness of future screening. To assess this influence we used an individual-based simulation model describing the relation between 14 HPV types and cervical disease, allowing the occurrence of multiple type infections. Screening scenarios f...

OBJECTIVE Effective data sharing is critical for comparative effectiveness research (CER), but there are significant concerns about inappropriate disclosure of patient data. These concerns have spurred the development of new technologies for privacy-preserving data sharing and data mining. Our goal is to review existing and emerging techniques that may be appropriate for data sharing related to...

BACKGROUND Burkina Faso introduced the Integrated Management of Childhood Illnesses (IMCI) strategy in 2003. However, an evaluation conducted in 2013 found that only 28 % of children were assessed for three danger signs as recommended by IMCI, and only 15 % of children were correctly classified. About 30 % of children were correctly prescribed with an antibiotic for suspected pneumonia or oral ...

hpv vaccine has been recently added to the iran drug list, so decision makers need information beyond that available from rcts to recommend funding for this vaccination. modeling and economic studies have addressed some of those information needs. we reviewed cost effectiveness studies to find a suitable model for iranian population to determine the potential cost effectiveness of hpv vaccine p...

the present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (iso 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to iso 15189.the quality management intervention based on iso 15189 was conceded through t...

OBJECTIVE This study assessed the cost effectiveness of different types of television and radio advertisements and the time of day in which advertisements were placed in generating calls to the Oregon tobacco quitline. DESIGN Cost effectiveness was measured by cost per call, calculated as the cost of advertising divided by the number of quitline calls generated by that advertising. Advertisin...

New medical technology is often cited as a contributing factor to increasing health care costs. In a 1990 report to the National Committee for Quality Health Care, 2 the forces driving health care spending were examined in detail. In a section reviewing the impact of new medical technology, the report cited an analysis of American Hospital Association data that concluded half the increase in re...

We study synchronization and noise-induced resonance phenomena in systems of globally coupled oscillators, each possessing finite inertia. The behavior of the order parameter, which measures the collective synchronization of the system, is investigated as the noise level and the coupling strength are varied, and hysteretic behavior is manifested. The power spectrum of the phase velocity is also...

We study effective spatial and angular correlations in beams of any state of spatial coherence, and we introduce a phase-space product, Q , which takes these correlations into account. This phase-space product is shown to reduce to the conventional beam-quality factor M(2) when the beam is spatially fully coherent. We also determine the lower bound for the value of Q and demonstrate that it is ...

OBJECTIVE Approximately 20-30% of all colorectal cancer (CRC) cases may have a familial contribution. The family history of CRC can be prominent (e.g., hereditary colorectal cancer (HCRC)) or more moderate (e.g., familial colorectal cancer (FCRC)). For family members at risk, colonoscopic surveillance is a well-established method to prevent both HCRC and FCRC, although the evidence for the exac...