When the Cardiac Society of Great Britain and Ireland met for the first time its initial task was to set up a committee to define the best location for a single chest electrocardiograph lead. The recommendations were agreed with the American Heart Association and a joint report was published in both countries and republished in the first issue of the British Heart Journal.' At that time the ele...

This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correlation of CACNA1C with Brugada and Bipolar suggests allelic disequilibrium, leading to a subpopulation of bipolar patients sensitive to arrhythmia.

A 62-year-old lady was admitted with clinical and electrocardiograph features of acute myocardial infarction. Urgent coronary arteriography was performed, demonstrating a single discrete stenosis of one coronary artery. Following intracoronary injection of GTN, this stenosis completely resolved, as the symptoms did. The causes of acute myocardial infarction with normal coronary arteries are rev...