In this study, electrochemical molecularly imprinted sensors were fabricated and used for the determination of ascorbic acid (AA). Nanofiber membranes of cellulose acetate (CA)/multi-walled carbon nanotubes (MWCNTs)/polyvinylpyrrolidone (PVP) (CA/MWCNTs/PVP) were prepared by electrospinning technique. After being transferred to a glass carbon electrode (GC), the nanofiber interface was further ...

Local Electrochemical Impedance Spectroscopy (LEIS) is an emerging discipline in the field of electrochemical research. It is based on the widely accepted Electrochemical Impedance Spectroscopy (EIS) technique, a powerful method to determine reaction mechanisms on macroscopic electrodes. When however the electrode represents a heterogeneous behavior, local information is indispensable. This pro...

Neurons release neurotransmitters in a process called exocytosis, wherein packets of transmitter molecules are released from the cells upon stimulation. Adrenal chromaffin cells, which also undergo exocytosis, constitute a model system for neuronal release. Quantal release of adrenaline from chromaffin cells can be measured using the electrochemical technique of amperometry, historically employ...

Electrochemistry in combination with mass spectrometry is emerging as a versatile analytical technique in the imitation of oxidative drug metabolism during the early stages of drug discovery and development. Here, we present electrochemical O-dealkylation of phenacetin to acetaminophen by square-wave potential pulses consisting of consecutive sub-second oxidation and reduction steps. This O-dea...

Simultaneous acquisition of in vivo electrophysiological and neurochemical information is essential for understanding how endogenous neurochemicals modulate the dynamics of brain activity. However, up to now such a task has rarely been accomplished due to the major technical challenge of operating two independent recording systems simultaneously in real-time. Here we propose a simpler solution ...

The electrochemical reduction mechanism of ethidium bromide was first studied by spectroelectrochemistry. This reduction was proved to be a two-step process by cyclic voltammetry, differential pulse voltammetry and spectroelectrochemistry, in which each step was proved to be a one-electron transfer process by a spectropotentiostatic fluorescence technique. Hydroethidine was confirmed to be the ...