While peripheral sensory neurons respond to natural stimuli with a broad range of spatiotemporal frequencies, central neurons instead respond sparsely to specific features in general. The nonlinear transformations leading to this emergent selectivity are not well understood. Here we characterized how the neural representation of stimuli changes across successive brain areas, using the electrose...

DNA lesions that block transcription may cause cell death even when repaired, if transcription does not restart to reestablish cellular metabolism. However, transcription resumption after individual DNA-lesion repair remains poorly described in mechanistic terms and its players are largely unknown. The general transcription factor II H (TFIIH) is a major actor of both nucleotide excision repair...

Fish in the family Mormyridae produce weak electric organ discharges that are used in orientation and communication. The peripheral and central anatomy of the electrosensory system has been well studied in the species Gnathonemus petersii, but comparative studies in other species are scarce. Here we report on one genus of mormyrid that displays a remarkable change in the electrosensory lateral ...

We introduce the notion of elementary Seely category as a notion of categorical model of Elementary Linear Logic (ELL) inspired from Seely’s definition of models of Linear Logic (LL). In order to deal with additive connectives in ELL, we use the approach of Danos and Joinet [DJ03]. From the categorical point of view, this requires us to go outside the usual interpretation of connectives by func...

This paper treats the privacy-preserving publication of social graphs in the presence of active adversaries, that is, adversaries with the ability to introduce sybil nodes in the graph prior to publication and leverage them to create unique fingerprints for a set of victim nodes and re-identify them after publication. Stemming from the notion of (k, l)-anonymity, we introduce (k, l)-anonymous t...

that holds in the same generality as the universal coefficient theorem of Rosenberg and Schochet. There are advantages, in some circumstances, to using HomΛ(K(A),K(B)) in place of KK(A,B). These advantages derive from the fact that K(A) can be equipped with order and scale structures similar to those on K0(A). With this additional structure, the “Λ−module” K(A) becomes a powerful invariant of C...

The least-loaded strategy (LL) is a built-in dynamic algorithm for the proposed standard CORBA Load Balancing and Monitoring Service. This paper describes this algorithm and identifies three improvement opportunities. We propose a strategy, called enhanced least-loaded (eLL), that incorporates the corresponding improvements. Simulation results demonstrate that eLL has potentially better average...

The ether-lipid 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine (ET-18-OCH3) has anticancer activity, but systemic toxicity has restricted its therapeutic use. In this report "free" ET-18-OCH3 and a stable, well-characterized, liposome-based formulation of ET-18-OCH3 (ELL-12) were compared for in vivo toxicity in normal mice and for therapeutic efficacy in three mouse tumor model systems. ...

A Correction to this paper has been published: https://doi.org/10.1140/epjc/s10052-020-7621-7.