The available literature on tobacco endgames tends to be limited to discussing means, targets and difficulties. This article offers additional ideas on the key elements of endgame strategies and the circumstances in which these are likely to be adopted and implemented. We suggest such strategies will include explicit plans, will define the nature of `the end of tobacco use/sale' and have target...

There are several approaches for using computers in deriving mathematical proofs. For their illustration, we provide an in-depth study of using computer support for proving one complex combinatorial conjecture – correctness of a strategy for the chess KRK endgame. The final, machine verifiable, result presented in this paper is that there is a winning strategy for white in the KRK endgame gener...

The effect of the 2-nitroimidazole Ro 03-8799 (8799) on the activity of 11 chemotherapeutic agents against the anaplastic MT tumour in mice has been determined by soft agar cloning. The 8799, whilst producing little cytotoxicity by itself, potentiated the cytotoxic actions of the alkylating agents melphalan and cyclophosphamide, and the nitrosoureas BCNU, CCNU and MeCCNU. This potentiation was ...

The simple two-person poker model, known as Basic Endgame, may be described as follows. With a certain probability known to both players, Player I is dealt a hand which is a sure winner. If it is not a sure winner, then Player II is sure to have a better hand. Player I may either check, in which case the better hand wins the antes, or bet. If Player I bets, Player II may either fold, conceeding...

Current constraints on spatial curvature show that it is dynamically negligible: |ΩK| . 5× 10−3 (95% CL). Neglecting it as a cosmological parameter would be premature however, as more stringent constraints on ΩK at around the 10 −4 level would offer valuable tests of eternal inflation models and probe novel large-scale structure phenomena. This precision also represents the “curvature floor”, b...

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We propose a simple modification to the rule governing how the dice game Left Center Right ends. The new rule extends the game in a natural way, and leads to some intriguing mathematical questions.

This is a report on the data-mining of two chess databases, the objective being to compare their sub-7-man content with perfect play as documented in Nalimov endgame tables. Van der Heijden’s ENDGAME STUDY DATABASE IV is a definitive collection of 76,132 studies in which White should have an essentially unique route to the stipulated goal. Chessbase’s BIG DATABASE 2010 holds some 4.5 million ga...